| Literature DB >> 2306624 |
Abstract
Injections of picomolar quantities of gastrin-17 into the hypothalamic paraventricular nucleus increased gastric acid output in anesthetized rats. The response was dose-dependent, and it was blocked by atropin and by vagotomy. The same doses, injected intravenously, intraventriculary or into sites far from the nucleus, did not increase the output. Cholecystokinin-8 injected into the nucleus had no effect on the acid output.Entities:
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Year: 1990 PMID： 2306624 DOI： 10.1016/0006-8993(90)90417-a
Source DB: PubMed Journal: Brain Res ISSN： 0006-8993 Impact factor: 3.252