Literature DB >> 23065368

Current treatment options for type 2 diabetes mellitus in youth: today's realities and lessons from the TODAY study.

Minu M George1, Kenneth C Copeland.   

Abstract

The incidence of type 2 diabetes in children and adolescents has increased over the last 2 decades, paralleled by an increase in obesity over the same time period. Although the value of lifestyle modification in obese youth is unquestioned, scant evidence for optimal treatment of type 2 diabetes in this age group exists. Despite recent therapeutic drug trials, metformin and insulin are the only medicines currently approved by the U.S. Food and Drug Administration for the treatment of type 2 diabetes in youth. Because of recently amended pharmaceutical regulations, however, it is likely that more antidiabetic medications soon will be added to the armamentarium of therapeutic options for youth with type 2 diabetes. Additionally, the recently published TODAY study comparing safety and efficacy of three treatment regimens in maintaining glycemic control in youth with type 2 diabetes has shed new light on the problem.

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Year:  2013        PMID： 23065368      PMCID： PMC3545061          DOI： 10.1007/s11892-012-0334-z

Source DB:  PubMed          Journal:  Curr Diab Rep        ISSN： 1534-4827            Impact factor:   4.810


  49 in total

Review 1.  Standards of medical care in diabetes--2012.

Authors: 
Journal:  Diabetes Care       Date:  2012-01       Impact factor: 19.112

Review 2.  The global spread of type 2 diabetes mellitus in children and adolescents.

Authors:  Orit Pinhas-Hamiel; Philip Zeitler
Journal:  J Pediatr       Date:  2005-05       Impact factor: 4.406

Review 3.  Insulin treatment in children and adolescents with diabetes.

Authors:  Hans-Jacob Bangstad; Thomas Danne; Larry Deeb; Przemyslawa Jarosz-Chobot; Tatsuhiko Urakami; Ragnar Hanas
Journal:  Pediatr Diabetes       Date:  2009-09       Impact factor: 4.866

Review 4.  Type 2 diabetes in pediatrics and adults: thoughts from a clinical pharmacology perspective.

Authors:  Jayabharathi Vaidyanathan; Sally Choe; Chandrahas G Sahajwalla
Journal:  J Pharm Sci       Date:  2012-03-01       Impact factor: 3.534

5.  The burden of diabetes mellitus among US youth: prevalence estimates from the SEARCH for Diabetes in Youth Study.

Authors:  Angela D Liese; Ralph B D'Agostino; Richard F Hamman; Patrick D Kilgo; Jean M Lawrence; Lenna L Liu; Beth Loots; Barbara Linder; Santica Marcovina; Beatriz Rodriguez; Debra Standiford; Desmond E Williams
Journal:  Pediatrics       Date:  2006-10       Impact factor: 7.124

Review 6.  Type 2 diabetes among North American children and adolescents: an epidemiologic review and a public health perspective.

Authors:  A Fagot-Campagna; D J Pettitt; M M Engelgau; N R Burrows; L S Geiss; R Valdez; G L Beckles; J Saaddine; E W Gregg; D F Williamson; K M Narayan
Journal:  J Pediatr       Date:  2000-05       Impact factor: 4.406

7.  Characteristics of adolescents and youth with recent-onset type 2 diabetes: the TODAY cohort at baseline.

Authors:  Kenneth C Copeland; Philip Zeitler; Mitchell Geffner; Cindy Guandalini; Janine Higgins; Kathryn Hirst; Francine R Kaufman; Barbara Linder; Santica Marcovina; Paul McGuigan; Laura Pyle; William Tamborlane; Steven Willi
Journal:  J Clin Endocrinol Metab       Date:  2010-10-20       Impact factor: 5.958

Review 8.  Morbid obesity in pediatric diabetes mellitus: surgical options and outcomes.

Authors:  Mary L Brandt; Carroll M Harmon; Michael A Helmrath; Thomas H Inge; Siripoom V McKay; Marc P Michalsky
Journal:  Nat Rev Endocrinol       Date:  2010-09-14       Impact factor: 43.330

Review 9.  Type 2 diabetes mellitus in children and youth: a new epidemic.

Authors:  Francine Ratner Kaufman
Journal:  J Pediatr Endocrinol Metab       Date:  2002-05       Impact factor: 1.634

10.  Incidence of diabetes in youth in the United States.

Authors:  Dana Dabelea; Ronny A Bell; Ralph B D'Agostino; Giuseppina Imperatore; Judith M Johansen; Barbara Linder; Lenna L Liu; Beth Loots; Santica Marcovina; Elizabeth J Mayer-Davis; David J Pettitt; Beth Waitzfelder
Journal:  JAMA       Date:  2007-06-27       Impact factor: 56.272
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  12 in total

1.  Reversal of type 2 diabetes in youth who adhere to a very-low-energy diet: a pilot study.

Authors:  Megan L Gow; Louise A Baur; Nathan A Johnson; Chris T Cowell; Sarah P Garnett
Journal:  Diabetologia       Date:  2016-11-26       Impact factor: 10.122

Review 2.  Bariatric Surgery for Adolescents with Type 2 Diabetes: an Emerging Therapeutic Strategy.

Authors:  M A Stefater; T H Inge
Journal:  Curr Diab Rep       Date:  2017-08       Impact factor: 4.810

Review 3.  New-onset diabetes after kidney transplant in children.

Authors:  Rouba Garro; Barry Warshaw; Eric Felner
Journal:  Pediatr Nephrol       Date:  2014-06-04       Impact factor: 3.714

Review 4.  Obesity and type 2 diabetes in children: epidemiology and treatment.

Authors:  Elizabeth R Pulgaron; Alan M Delamater
Journal:  Curr Diab Rep       Date:  2014-08       Impact factor: 4.810

5.  Effects of the glucagon-like peptide-1 receptor agonist liraglutide in juvenile transgenic pigs modeling a pre-diabetic condition.

Authors:  Elisabeth Streckel; Christina Braun-Reichhart; Nadja Herbach; Maik Dahlhoff; Barbara Kessler; Andreas Blutke; Andrea Bähr; Nicole Übel; Matthias Eddicks; Mathias Ritzmann; Stefan Krebs; Burkhard Göke; Helmut Blum; Rüdiger Wanke; Eckhard Wolf; Simone Renner
Journal:  J Transl Med       Date:  2015-02-25       Impact factor: 5.531

Review 6.  Lifestyle therapy for the treatment of youth with type 2 diabetes.

Authors:  Jonathan McGavock; Allison Dart; Brandy Wicklow
Journal:  Curr Diab Rep       Date:  2015-01       Impact factor: 4.810

7.  Design, implementation, and evaluation of a pediatric and adolescent type 2 diabetes management program at a tertiary pediatric center.

Authors:  M Constantine Samaan; Marlie Valencia; Connie Cheung; Boguslaw Wilk; Keith Lau; Lehana Thabane
Journal:  J Multidiscip Healthc       Date:  2014-07-31

8.  Response to comments on: Butler et al. Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumors. Diabetes 2013;62:2595-2604.

Authors:  Alexandra E Butler; Martha Campbell-Thompson; Tatyana Gurlo; David W Dawson; Mark Atkinson; Peter C Butler
Journal:  Diabetes       Date:  2013-10       Impact factor: 9.461

9.  Treatment regimens and glycosylated hemoglobin levels in youth with Type 1 and Type 2 diabetes: Data from SEARCH (United States) and YDR (India) registries.

Authors:  Anandakumar Amutha; Pradeep A Praveen; Christine W Hockett; Toan C Ong; Elizabeth T Jensen; Scott P Isom; Ralph B Jr D'Agostino; Richard F Hamman; Elizabeth J Mayer-Davis; Raj Paul Wadwa; Jean M Lawrence; Catherine Pihoker; Michael G Kahn; Dana Dabelea; Nikhil Tandon; Viswanathan Mohan
Journal:  Pediatr Diabetes       Date:  2020-03-24       Impact factor: 3.409

10.  MicroRNAs in Hyperglycemia Induced Endothelial Cell Dysfunction.

Authors:  Maskomani Silambarasan; Jun Rong Tan; Dwi Setyowati Karolina; Arunmozhiarasi Armugam; Charanjit Kaur; Kandiah Jeyaseelan
Journal:  Int J Mol Sci       Date:  2016-04-07       Impact factor: 5.923
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