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Literature DB >> 23065270

Novel single nucleotide polymorphisms of bovine SREBP1 gene is association with fatty acid composition and marbling score in commercial Korean cattle (Hanwoo).

Yoonseok Lee¹, Dongyep Oh, Jeayoung Lee, Boomi La, Jungsou Yeo.

Abstract

The sterol regulatory element binding factor 1 (SREBP1) gene plays an important role in the biosynthesis of fatty acids. The aim of this study was to investigate the association between SNPs within SREBP1 gene and fatty acid composition of muscle fat and marbling score in a commercial population of Korean cattle. Among 10 SNPs in dbSNP of bovine SREBP1 gene, we identified 7 polymorphic SNPs and 84-bp ins/del variation (SREBP1-INT5 SNP) in commercial Korean cattle (n = 513). The SREBP1-9 SNP showed a significant effect on marbling score, monounsaturated fatty acids and C18:1n-9 in the muscle fat of commercial Korean cattle. However, SREBP1-INT5 SNP showed no effect on any fatty acid composition. Therefore, two polymorphisms in SREBP1 may improve flavored beef and meat quality in commercial Korean cattle.

Entities: Chemical Gene Species

Mesh：

Substances：

Year: 2012 PMID： 23065270 DOI： 10.1007/s11033-012-2055-4

Source DB: PubMed Journal: Mol Biol Rep ISSN： 0301-4851 Impact factor: 2.316

33 in total

Review 1. Structure, mechanism, and evolution of the mRNA capping apparatus.

Authors: S Shuman
Journal: Prog Nucleic Acid Res Mol Biol Date: 2001

Review 2. Sterol regulatory element-binding proteins (SREBPs): transcriptional regulators of lipid synthetic genes.

Authors: H Shimano
Journal: Prog Lipid Res Date: 2001-11 Impact factor: 16.195

3. Effect of pasture vs. concentrate feeding with or without antioxidants on carcass characteristics, fatty acid composition, and quality of Uruguayan beef.

Authors: C E Realini; S K Duckett; G W Brito; M Dalla Rizza; D De Mattos
Journal: Meat Sci Date: 2004-03 Impact factor: 5.209

4. Identification of marbling-related candidate genes in M. longissimus dorsi of high- and low marbled Hanwoo (Korean Native Cattle) steers.

Authors: Seung-Hwan Lee; Yong-Min Cho; Sang-Hong Lee; Bum-Soo Kim; Nam-Kuk Kim; Yeon-Ho Choy; Kyoung-Hoon Kim; Duhak Yoon; Seok-Ki Im; Sung-Jong Oh; Eung-Woo Park
Journal: BMB Rep Date: 2008-12-31 Impact factor: 4.778

Review 5. Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's been.

Authors: Timothy F Osborne; Peter J Espenshade
Journal: Genes Dev Date: 2009-11-15 Impact factor: 11.361

6. The polymorphisms of stearoyl-CoA desaturase (SCD1) and sterol regulatory element binding protein-1 (SREBP-1) genes and their association with the fatty acid profile of muscle and subcutaneous fat in Fleckvieh bulls.

Authors: L Barton; T Kott; D Bures; D Rehák; R Zahrádková; B Kottová
Journal: Meat Sci Date: 2009-11-26 Impact factor: 5.209

1. Breed dependent regulatory mechanisms of beneficial and non-beneficial fatty acid profiles in subcutaneous adipose tissue in cattle with divergent feed efficiency.

Authors: Mi Zhou; Zhi Zhu; Hui-Zeng Sun; Ke Zhao; Mike E R Dugan; Heather Bruce; Carolyn Fitzsimmons; Changxi Li; Le Luo Guan
Journal: Sci Rep Date: 2022-03-17 Impact factor: 4.996

1 in total

Novel single nucleotide polymorphisms of bovine SREBP1 gene is association with fatty acid composition and marbling score in commercial Korean cattle (Hanwoo).

Review 1. Structure, mechanism, and evolution of the mRNA capping apparatus.

Review 2. Sterol regulatory element-binding proteins (SREBPs): transcriptional regulators of lipid synthetic genes.

3. Effect of pasture vs. concentrate feeding with or without antioxidants on carcass characteristics, fatty acid composition, and quality of Uruguayan beef.

4. Identification of marbling-related candidate genes in M. longissimus dorsi of high- and low marbled Hanwoo (Korean Native Cattle) steers.

Review 5. Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's been.

6. The polymorphisms of stearoyl-CoA desaturase (SCD1) and sterol regulatory element binding protein-1 (SREBP-1) genes and their association with the fatty acid profile of muscle and subcutaneous fat in Fleckvieh bulls.

Review 7. Identification and utilization of genes associated with beef qualities.

8. Acetyl-CoA carboxylase beta gene is regulated by sterol regulatory element-binding protein-1 in liver.

Review 9. Expression and nutritional regulation of lipogenic genes in the ruminant lactating mammary gland.

10. Effect of SCD and SREBP genotypes on fatty acid composition in adipose tissue of Japanese Black cattle herds.

1. Breed dependent regulatory mechanisms of beneficial and non-beneficial fatty acid profiles in subcutaneous adipose tissue in cattle with divergent feed efficiency.