PURPOSE: The purpose of this systematic review and meta-analysis was to examine the literature and identify randomized controlled trials (RCTs), in order to answer if performing follicular flushing during the oocyte retrieval may improve the assisted reproductive technologies (ART) outcomes. METHODS: An exhaustive electronic search was performed using MEDLINE and EMBASE databases. Only RCTs comparing follicular flushing to aspiration only during ART, were included. We included 5 trials, with a total of 482 patients randomized, with median ages ranging from 30.5 to 37.1. RESULTS: The data analyses did not show significant differences regarding live birth rate, clinical pregnancies rates, and the number of oocytes retrieved. The duration of oocyte retrieval was significantly increased in the follicular flushing group. CONCLUSIONS: The results from this systematic review and meta-analysis suggest that there is no advantage to use of routine follicular flushing during OR in an unselected group of patients.
PURPOSE: The purpose of this systematic review and meta-analysis was to examine the literature and identify randomized controlled trials (RCTs), in order to answer if performing follicular flushing during the oocyte retrieval may improve the assisted reproductive technologies (ART) outcomes. METHODS: An exhaustive electronic search was performed using MEDLINE and EMBASE databases. Only RCTs comparing follicular flushing to aspiration only during ART, were included. We included 5 trials, with a total of 482 patients randomized, with median ages ranging from 30.5 to 37.1. RESULTS: The data analyses did not show significant differences regarding live birth rate, clinical pregnancies rates, and the number of oocytes retrieved. The duration of oocyte retrieval was significantly increased in the follicular flushing group. CONCLUSIONS: The results from this systematic review and meta-analysis suggest that there is no advantage to use of routine follicular flushing during OR in an unselected group of patients.
Authors: Anna L M Souza; Marcos Sampaio; Graciele B Noronha; Ludiana G R Coster; Roberta S G de Oliveira; Selmo Geber Journal: J Assist Reprod Genet Date: 2017-07-21 Impact factor: 3.412
Authors: Marcelo Marinho de Souza; Ana Cristina Allemand Mancebo; Maria do Carmo Borges de Souza; Roberto de Azevedo Antunes; Ana Luiza Barbeitas; Verônica de Almeida Raupp; Layna Almeida Barbosa da Silva; Flávia Siqueira; Ana Luisa Bruno Marinho de Souza Journal: JBRA Assist Reprod Date: 2021-04-27
Authors: A S Kohl Schwartz; I Calzaferri; M Roumet; A Limacher; A Fink; A Wueest; S Weidlinger; V R Mitter; B Leeners; M Von Wolff Journal: Hum Reprod Date: 2020-10-01 Impact factor: 6.918