Literature DB >> 23065017

Acute stroke after intravitreal bevacizumab to treat choroidal neovascularization due to angioid streaks in pseudoxanthoma elasticum : a severe systemic adverse event after an off-label procedure.

Gianluca Besozzi1, Andrea Ferrara, Enrico Epifani, Daniela Intini, Margherita Apruzzese, Antonio Provenzano, Michele Vetrugno.   

Abstract

To report the occurrence of acute stroke after intravitreal bevacizumab administration to treat choroidal neovascularization due to angioid streaks in a patient affected by pseudoxanthoma elasticum. A 54-year-old man with pseudoxanthoma elasticum had vision loss because of choroidal neovascularization due to angioid streaks. He underwent two intravitreal bevacizumab injections. Three days after the second procedure the patient was afflicted by acute stroke. Intravitreal injection of bevacizumab to treat choroidal neovascularization due to angioid streaks in pseudoxanthoma elasticum could lead to severe systemic adverse events.

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Year:  2012        PMID: 23065017     DOI: 10.1007/s10792-012-9647-9

Source DB:  PubMed          Journal:  Int Ophthalmol        ISSN: 0165-5701            Impact factor:   2.031


  19 in total

1.  Angioid streaks. I. Ophthalmoscopic variations and diagnostic problems.

Authors:  J A Shields; J L Federman; T L Tomer; W H Annesley
Journal:  Br J Ophthalmol       Date:  1975-05       Impact factor: 4.638

2.  Intravitreal bevacizumab for choroidal neovascularization secondary to angioid streaks.

Authors:  Michele Rinaldi; Roberto Dell'Omo; Mario R Romano; Flavia Chiosi; Ugo Cipollone; Ciro Costagliola
Journal:  Arch Ophthalmol       Date:  2007-10

3.  Macular translocation for subfoveal choroidal neovascularization in angioid streaks.

Authors:  D B Roth; M Estafanous; H Lewis
Journal:  Am J Ophthalmol       Date:  2001-03       Impact factor: 5.258

4.  Prevalence of symptomatic intracranial aneurysm and ischaemic stroke in pseudoxanthoma elasticum.

Authors:  J S van den Berg; R C Hennekam; J R Cruysberg; P M Steijlen; J Swart; N Tijmes; M Limburg
Journal:  Cerebrovasc Dis       Date:  2000 Jul-Aug       Impact factor: 2.762

5.  Verteporfin photodynamic therapy of choroidal neovascularization in angioid streaks: one-year results of a prospective case series.

Authors:  Andrew C Browning; A K K Chung; F Ghanchi; S P Harding; M Musadiq; S J Talks; Y C Yang; W M Amoaku
Journal:  Ophthalmology       Date:  2005-07       Impact factor: 12.079

Review 6.  Angioid streaks.

Authors:  J G Clarkson; R D Altman
Journal:  Surv Ophthalmol       Date:  1982 Mar-Apr       Impact factor: 6.048

Review 7.  Pseudoxanthoma elasticum: a clinical, pathophysiological and genetic update including 11 novel ABCC6 mutations.

Authors:  N Chassaing; L Martin; P Calvas; M Le Bert; A Hovnanian
Journal:  J Med Genet       Date:  2005-05-13       Impact factor: 6.318

8.  Ranibizumab and bevacizumab for neovascular age-related macular degeneration.

Authors:  Daniel F Martin; Maureen G Maguire; Gui-shuang Ying; Juan E Grunwald; Stuart L Fine; Glenn J Jaffe
Journal:  N Engl J Med       Date:  2011-04-28       Impact factor: 91.245

9.  Long-term control of choroidal neovascularisation secondary to angioid streaks treated with intravitreal bevacizumab (Avastin).

Authors:  P Neri; S Salvolini; C Mariotti; L Mercanti; S Celani; A Giovannini
Journal:  Br J Ophthalmol       Date:  2008-10-29       Impact factor: 4.638

10.  Ranibizumab versus bevacizumab to treat neovascular age-related macular degeneration: one-year findings from the IVAN randomized trial.

Authors:  Usha Chakravarthy; Simon P Harding; Chris A Rogers; Susan M Downes; Andrew J Lotery; Sarah Wordsworth; Barnaby C Reeves
Journal:  Ophthalmology       Date:  2012-05-11       Impact factor: 12.079

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  3 in total

1.  Intravitreal Bevacizumab for Choroidal Neovascularization Associated with Angioid Streaks: Long-term Results.

Authors:  T Lekha; Hari Narayan Prasad; Renuka Nikit Sarwate; Manasi Patel; S Karthikeyan
Journal:  Middle East Afr J Ophthalmol       Date:  2017 Jul-Sep

2.  The need for pharmacovigilance in ophthalmic practice.

Authors:  Sundaram Natarajan
Journal:  Indian J Ophthalmol       Date:  2016-03       Impact factor: 1.848

3.  Relief Effect of Bevacizumab on Severe Edema Induced by Re-irradiation in Brain Tumor Patients.

Authors:  Ge Shen; Ying-Jie Wang; Yan-Jun Guan; Da-Peng Dong; Gang Yang; Dan Li; Rui-Min Hao; Hui-Ru Sun; Ming Zhou; Kun-Peng Wang; Shi-Xiang Zhou; Qin-Wen Wang; Shi-Kai Wu; Yan-Jun Zeng
Journal:  Chin Med J (Engl)       Date:  2015-08-05       Impact factor: 2.628

  3 in total

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