D L Rotstein1, R I Aviv, B J Murray. 1. Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Canada.
Abstract
BACKGROUND: Few studies to date have captured perfusion and vascular permeability changes during a migraineur's aura. This may be important information to the clinician in the context of the differential diagnosis of migraine with aura versus acute stroke. SUMMARY: We report a case in which magnetic resonance perfusion during a migraine aura showed unilateral hypoperfusion differentially affecting gray and white matter and was associated with a hemispheric increase in permeability. CONCLUSIONS: Imaging in this case suggests that migraine aura is associated with oligemia below the threshold for infarction. Increased vascular permeability may be a critical mechanism contributing to perfusion changes observed in migraine with aura.
BACKGROUND: Few studies to date have captured perfusion and vascular permeability changes during a migraineur's aura. This may be important information to the clinician in the context of the differential diagnosis of migraine with aura versus acute stroke. SUMMARY: We report a case in which magnetic resonance perfusion during a migraine aura showed unilateral hypoperfusion differentially affecting gray and white matter and was associated with a hemispheric increase in permeability. CONCLUSIONS: Imaging in this case suggests that migraine aura is associated with oligemia below the threshold for infarction. Increased vascular permeability may be a critical mechanism contributing to perfusion changes observed in migraine with aura.
Authors: Benjamin M Ellingson; Chelsea Hesterman; Mollie Johnston; Nicholas R Dudeck; Andrew C Charles; Juan Pablo Villablanca Journal: Neuroimaging Clin N Am Date: 2019-02-19 Impact factor: 2.264