Literature DB >> 23064103

The NLRP4-DTX4 axis: a key suppressor of TBK1 and innate antiviral signaling.

Soratree Charoenthongtrakul1, Linlin Gao, Edward W Harhaj.   

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Year:  2012        PMID： 23064103      PMCID： PMC3527092          DOI： 10.1038/cmi.2012.49

Source DB:  PubMed          Journal:  Cell Mol Immunol        ISSN： 1672-7681            Impact factor:   11.530


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  12 in total

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6.  TAX1BP1 and A20 inhibit antiviral signaling by targeting TBK1-IKKi kinases.

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7.  De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling.

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9.  The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response.

Authors:  Constantin S Friedman; Marie Anne O'Donnell; Diana Legarda-Addison; Aylwin Ng; Washington B Cárdenas; Jacob S Yount; Thomas M Moran; Christopher F Basler; Akihiko Komuro; Curt M Horvath; Ramnik Xavier; Adrian T Ting
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1.  The NLR family pyrin domain-containing 11 protein contributes to the regulation of inflammatory signaling.

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2.  DDX3X Links NLRP11 to the Regulation of Type I Interferon Responses and NLRP3 Inflammasome Activation.

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  2 in total

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