Literature DB >> 23063464

Beside the MEF2 axis: unconventional functions of HDAC4.

Andrea Clocchiatti1, Eros Di Giorgio, Francesca Demarchi, Claudio Brancolini.   

Abstract

The class IIa deacetylase HDAC4 is unequivocally known as a negative regulator of MEF2-dependent transcription. In the past years several works have allowed us to understand how different signals, mirroring specific environmental circumstances keep in check the repressive action of HDAC4 against MEF2s. At the same time, pieces of evidence have gradually accumulated about HDAC4 activities emancipated from MEF2s. The aim of this review is to discuss about these "unconventional functions" of HDAC4.
Copyright © 2012 Elsevier Inc. All rights reserved.

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Year:  2012        PMID： 23063464     DOI： 10.1016/j.cellsig.2012.10.002

Source DB:  PubMed          Journal:  Cell Signal        ISSN： 0898-6568            Impact factor:   4.315


  11 in total

Review 1.  Selective class IIa HDAC inhibitors: myth or reality.

Authors:  Eros Di Giorgio; Enrico Gagliostro; Claudio Brancolini
Journal:  Cell Mol Life Sci       Date:  2014-09-05       Impact factor: 9.261

2.  Investigation of differential HDAC4 methylation patterns in eating disorders.

Authors:  Subha Subramanian; Patricia R Braun; Shizhong Han; James B Potash
Journal:  Psychiatr Genet       Date:  2018-02       Impact factor: 2.458

3.  MicroRNA-140 Provides Robustness to the Regulation of Hypertrophic Chondrocyte Differentiation by the PTHrP-HDAC4 Pathway.

Authors:  Garyfallia Papaioannou; Fatemeh Mirzamohammadi; Thomas S Lisse; Shigeki Nishimori; Marc N Wein; Tatsuya Kobayashi
Journal:  J Bone Miner Res       Date:  2015-06       Impact factor: 6.741

Review 4.  Histone deacetylase 4 (HDAC4): a new player in anorexia nervosa?

Authors:  Mari Sild; Linda Booij
Journal:  Mol Psychiatry       Date:  2019-02-11       Impact factor: 15.992

5.  Eating disorder predisposition is associated with ESRRA and HDAC4 mutations.

Authors:  Huxing Cui; Jarrette Moore; Sunbola S Ashimi; Brittany L Mason; Jordan N Drawbridge; Shizhong Han; Benjamin Hing; Abigail Matthews; Carrie J McAdams; Benjamin W Darbro; Andrew A Pieper; David A Waller; Chao Xing; Michael Lutter
Journal:  J Clin Invest       Date:  2013-11       Impact factor: 14.808

6.  MEF2 is a converging hub for histone deacetylase 4 and phosphatidylinositol 3-kinase/Akt-induced transformation.

Authors:  Eros Di Giorgio; Andrea Clocchiatti; Sara Piccinin; Andrea Sgorbissa; Giulia Viviani; Paolo Peruzzo; Salvatore Romeo; Sabrina Rossi; Angelo Paolo Dei Tos; Roberta Maestro; Claudio Brancolini
Journal:  Mol Cell Biol       Date:  2013-09-16       Impact factor: 4.272

7.  Up-regulation of HDAC4 is associated with Schwann cell proliferation after sciatic nerve crush.

Authors:  Yonghua Liu; Yang Liu; Xiaoke Nie; Jianhua Cao; Xiaojian Zhu; Weidong Zhang; Zhongbing Liu; Xingxing Mao; Shixian Yan; Yingjie Ni; Youhua Wang
Journal:  Neurochem Res       Date:  2014-08-08       Impact factor: 3.996

8.  Unscheduled HDAC4 repressive activity in human fibroblasts triggers TP53-dependent senescence and favors cell transformation.

Authors:  Harikrishnareddy Paluvai; Eros Di Giorgio; Claudio Brancolini
Journal:  Mol Oncol       Date:  2018-11-14       Impact factor: 6.603

9.  Electrical Stimulation Improves Rat Muscle Dysfunction Caused by Chronic Intermittent Hypoxia-Hypercapnia via Regulation of miRNA-Related Signaling Pathways.

Authors:  Lu-Lu Pan; Jiang-Qiong Ke; Cui-Cui Zhao; Shi-Yuan Huang; Jie Shen; Xian-Xun Jiang; Xiao-Tong Wang
Journal:  PLoS One       Date:  2016-03-29       Impact factor: 3.240

10.  AKH-FOXO pathway regulates starvation-induced sleep loss through remodeling of the small ventral lateral neuron dorsal projections.

Authors:  Qiankun He; Juan Du; Liya Wei; Zhangwu Zhao
Journal:  PLoS Genet       Date:  2020-10-26       Impact factor: 5.917
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