Literature DB >> 23061884

Unexpected C-C bond cleavage: a route to 3,6-diarylpyridazines and 6-arylpyridazin-3-ones from 1,3-dicarbonyl compounds and methyl ketones.

Qinghe Gao1, Yanping Zhu, Mi Lian, Meicai Liu, Jingjing Yuan, Guodong Yin, Anxin Wu.   

Abstract

An unexpected C-C bond cleavage has been revealed in the absence of metal. This observation has been exploited to develop an efficient approach toward 3,6-diarylpyridazines and 6-arylpyridazin-3-ones from simple and commercially available 1,3-dicarbonyl compounds and methyl ketones.

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Year:  2012        PMID： 23061884     DOI： 10.1021/jo301751e

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  4 in total

Review 1.  Metal-Free Catalysis in C-C Single-Bond Cleavage: Achievements and Prospects.

Authors:  Mohit L Deb; B Shriya Saikia; Iftakur Rahman; Pranjal Kumar Baruah
Journal:  Top Curr Chem (Cham)       Date:  2022-08-11

2.  Scope and limitation of propylene carbonate as a sustainable solvent in the Suzuki-Miyaura reaction.

Authors:  Andrea Czompa; Balázs László Pásztor; Jennifer Alizadeh Sahar; Zoltán Mucsi; Dóra Bogdán; Krisztina Ludányi; Zoltán Varga; István M Mándity
Journal:  RSC Adv       Date:  2019-11-20       Impact factor: 4.036

3.  Multi Component Reactions under Increased Pressure: On the Mechanism of Formation of Pyridazino[5,4,3-de][1,6]naphthyridine Derivatives by the Reaction of Malononitrile, Aldehydes and 2-Oxoglyoxalarylhydrazones in Q-Tubes.

Authors:  Majdah A Al-Johani; Khadijah M Al-Zaydi; Sameera M Mousally; Norah F Alqahtani; Noha Hilmy Elnagdi; Mohamed H Elnagdi
Journal:  Molecules       Date:  2017-12-01       Impact factor: 4.411

4.  Synthesis of Pyridazine Derivatives by Suzuki-Miyaura Cross-Coupling Reaction and Evaluation of Their Optical and Electronic Properties through Experimental and Theoretical Studies.

Authors:  Sara S M Fernandes; João Aires-de-Sousa; Michael Belsley; M Manuela M Raposo
Journal:  Molecules       Date:  2018-11-18       Impact factor: 4.411
  4 in total

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