Literature DB >> 23060613

An ensemble correlation-based gene selection algorithm for cancer classification with gene expression data.

Yongjun Piao1, Minghao Piao, Kiejung Park, Keun Ho Ryu.   

Abstract

MOTIVATION: Gene selection for cancer classification is one of the most important topics in the biomedical field. However, microarray data pose a severe challenge for computational techniques. We need dimension reduction techniques that identify a small set of genes to achieve better learning performance. From the perspective of machine learning, the selection of genes can be considered to be a feature selection problem that aims to find a small subset of features that has the most discriminative information for the target.
RESULTS: In this article, we proposed an Ensemble Correlation-Based Gene Selection algorithm based on symmetrical uncertainty and Support Vector Machine. In our method, symmetrical uncertainty was used to analyze the relevance of the genes, the different starting points of the relevant subset were used to generate the gene subsets and the Support Vector Machine was used as an evaluation criterion of the wrapper. The efficiency and effectiveness of our method were demonstrated through comparisons with other feature selection techniques, and the results show that our method outperformed other methods published in the literature.

Entities:  

Mesh:

Year:  2012        PMID: 23060613     DOI: 10.1093/bioinformatics/bts602

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  14 in total

1.  Integrative analysis of DNA methylation and gene expression identified cervical cancer-specific diagnostic biomarkers.

Authors:  Wanxue Xu; Mengyao Xu; Longlong Wang; Wei Zhou; Rong Xiang; Yi Shi; Yunshan Zhang; Yongjun Piao
Journal:  Signal Transduct Target Ther       Date:  2019-12-13

2.  A Self-Training Subspace Clustering Algorithm under Low-Rank Representation for Cancer Classification on Gene Expression Data.

Authors:  Chun-Qiu Xia; Ke Han; Yong Qi; Yang Zhang; Dong-Jun Yu
Journal:  IEEE/ACM Trans Comput Biol Bioinform       Date:  2017-06-06       Impact factor: 3.710

3.  Machine learning-based differential network analysis: a study of stress-responsive transcriptomes in Arabidopsis.

Authors:  Chuang Ma; Mingming Xin; Kenneth A Feldmann; Xiangfeng Wang
Journal:  Plant Cell       Date:  2014-02-11       Impact factor: 11.277

4.  Novel tumor suppressor SPRYD4 inhibits tumor progression in hepatocellular carcinoma by inducing apoptotic cell death.

Authors:  Kashif Rafiq Zahid; Shiming Han; Fuling Zhou; Umar Raza
Journal:  Cell Oncol (Dordr)       Date:  2018-09-20       Impact factor: 7.051

5.  GSEA-SDBE: A gene selection method for breast cancer classification based on GSEA and analyzing differences in performance metrics.

Authors:  Hu Ai
Journal:  PLoS One       Date:  2022-04-26       Impact factor: 3.752

6.  Identification of Tumor Microenvironment and DNA Methylation-Related Prognostic Signature for Predicting Clinical Outcomes and Therapeutic Responses in Cervical Cancer.

Authors:  Bangquan Liu; Jiabao Zhai; Wanyu Wang; Tianyu Liu; Chang Liu; Xiaojie Zhu; Qi Wang; Wenjing Tian; Fubin Zhang
Journal:  Front Mol Biosci       Date:  2022-04-19

7.  Multi-class BCGA-ELM based classifier that identifies biomarkers associated with hallmarks of cancer.

Authors:  Vasily Sachnev; Saras Saraswathi; Rashid Niaz; Andrzej Kloczkowski; Sundaram Suresh
Journal:  BMC Bioinformatics       Date:  2015-05-20       Impact factor: 3.169

8.  Comparing the normalization methods for the differential analysis of Illumina high-throughput RNA-Seq data.

Authors:  Peipei Li; Yongjun Piao; Ho Sun Shon; Keun Ho Ryu
Journal:  BMC Bioinformatics       Date:  2015-10-28       Impact factor: 3.169

9.  A kernel-based multivariate feature selection method for microarray data classification.

Authors:  Shiquan Sun; Qinke Peng; Adnan Shakoor
Journal:  PLoS One       Date:  2014-07-21       Impact factor: 3.240

10.  Compensation of feature selection biases accompanied with improved predictive performance for binary classification by using a novel ensemble feature selection approach.

Authors:  Ursula Neumann; Mona Riemenschneider; Jan-Peter Sowa; Theodor Baars; Julia Kälsch; Ali Canbay; Dominik Heider
Journal:  BioData Min       Date:  2016-11-18       Impact factor: 2.522

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.