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Literature DB >> 23058805

Programmed cell death: a new way worms get rid of unwanted cells.

Abstract

The genetics and predictable cell death lineages in Caenorhabditis elegans have been critical for identifying a conserved apoptosis pathway. Yet, cells still die in mutants that disrupt this pathway. A recent study shows that this death occurs by cell shedding.

Entities: Chemical Disease Gene Species

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Year: 2012 PMID： 23058805 PMCID： PMC3618969 DOI： 10.1016/j.cub.2012.08.013

Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834

20 in total

1. An epithelial cell destined for apoptosis signals its neighbors to extrude it by an actin- and myosin-dependent mechanism.

Authors: J Rosenblatt; M C Raff; L P Cramer
Journal: Curr Biol Date: 2001-11-27 Impact factor: 10.834

Review 2. Epidermal morphogenesis.

Authors: Andrew D Chisholm; Jeff Hardin
Journal: WormBook Date: 2005-12-01

3. The C. elegans MELK ortholog PIG-1 regulates cell size asymmetry and daughter cell fate in asymmetric neuroblast divisions.

Authors: Shaun Cordes; C Andrew Frank; Gian Garriga
Journal: Development Date: 2006-06-14 Impact factor: 6.868

4. Bcl-2 inhibits ischemia-reperfusion-induced apoptosis in the intestinal epithelium of transgenic mice.

Authors: C M Coopersmith; D O'Donnell; J I Gordon
Journal: Am J Physiol Date: 1999-03

5. A serine/threonine kinase gene defective in Peutz-Jeghers syndrome.

Authors: A Hemminki; D Markie; I Tomlinson; E Avizienyte; S Roth; A Loukola; G Bignell; W Warren; M Aminoff; P Höglund; H Järvinen; P Kristo; K Pelin; M Ridanpää; R Salovaara; T Toro; W Bodmer; S Olschwang; A S Olsen; M R Stratton; A de la Chapelle; L A Aaltonen
Journal: Nature Date: 1998-01-08 Impact factor: 49.962

Programmed cell death: a new way worms get rid of unwanted cells.

1. An epithelial cell destined for apoptosis signals its neighbors to extrude it by an actin- and myosin-dependent mechanism.

Review 2. Epidermal morphogenesis.

3. The C. elegans MELK ortholog PIG-1 regulates cell size asymmetry and daughter cell fate in asymmetric neuroblast divisions.

4. Bcl-2 inhibits ischemia-reperfusion-induced apoptosis in the intestinal epithelium of transgenic mice.

5. A serine/threonine kinase gene defective in Peutz-Jeghers syndrome.

6. Control of adhesion-dependent cell survival by focal adhesion kinase.

Review 7. Genetics of programmed cell death in C. elegans: past, present and future.

8. Genetic control of programmed cell death in the nematode C. elegans.

Review 9. Programmed cell death in Caenorhabditis elegans.

10. Programmed elimination of cells by caspase-independent cell extrusion in C. elegans.

Review 1. Programmed cell death and clearance of cell corpses in Caenorhabditis elegans.