Literature DB >> 23055906

Women and epilepsy.

Sunila E O'Connor1, Mary L Zupanc.   

Abstract

Women with epilepsy face additional challenges when compared to their peers. Hormonal influences may increase seizure activity, alter endocrine function, and affect fertility. In this population, antiepileptic drugs (AEDs) reduce the efficacy of contraception methods and increase the risk of fetal malformations. Other pertinent issues to women with epilepsy include breastfeeding as well as bone mineral health. This article summarizes our current, collective knowledge of these issues and makes specific recommendations with respect to management.

Entities:  

Keywords:  antiepileptic drugs; breastfeeding; epilepsy; female; review; treatment

Year:  2009        PMID: 23055906      PMCID: PMC3460796          DOI: 10.5863/1551-6776-14.4.212

Source DB:  PubMed          Journal:  J Pediatr Pharmacol Ther        ISSN: 1551-6776


  94 in total

1.  The risk of spina bifida aperta after first-trimester exposure to valproate in a prenatal cohort.

Authors:  J G Omtzigt; F J Los; D E Grobbee; L Pijpers; M G Jahoda; H Brandenburg; P A Stewart; H L Gaillard; E S Sachs; J W Wladimiroff
Journal:  Neurology       Date:  1992-04       Impact factor: 9.910

Review 2.  Epilepsy-related injuries.

Authors:  Elaine C Wirrell
Journal:  Epilepsia       Date:  2006       Impact factor: 5.864

3.  Maternal use of antiepileptic drugs and the risk of major congenital malformations: a joint European prospective study of human teratogenesis associated with maternal epilepsy.

Authors:  E B Samrén; C M van Duijn; S Koch; V K Hiilesmaa; H Klepel; A H Bardy; G B Mannagetta; A W Deichl; E Gaily; M L Granström; H Meinardi; D E Grobbee; A Hofman; D Janz; D Lindhout
Journal:  Epilepsia       Date:  1997-09       Impact factor: 5.864

Review 4.  Drug metabolism in pregnancy, infancy and childhood.

Authors:  E Perucca
Journal:  Pharmacol Ther       Date:  1987       Impact factor: 12.310

5.  How common is catamenial epilepsy?

Authors:  S Duncan; C L Read; M J Brodie
Journal:  Epilepsia       Date:  1993 Sep-Oct       Impact factor: 5.864

6.  Guidelines for the care of women of childbearing age with epilepsy. Commission on Genetics, Pregnancy, and the Child, International League Against Epilepsy.

Authors: 
Journal:  Epilepsia       Date:  1993 Jul-Aug       Impact factor: 5.864

7.  Age-specific incidence and prevalence rates of treated epilepsy in an unselected population of 2,052,922 and age-specific fertility rates of women with epilepsy.

Authors:  H Wallace; S Shorvon; R Tallis
Journal:  Lancet       Date:  1998 Dec 19-26       Impact factor: 79.321

8.  Polycystic ovaries and hyperandrogenism in women taking valproate for epilepsy.

Authors:  J I Isojärvi; T J Laatikainen; A J Pakarinen; K T Juntunen; V V Myllylä
Journal:  N Engl J Med       Date:  1993-11-04       Impact factor: 91.245

9.  Progesterone therapy in women with complex partial and secondary generalized seizures.

Authors:  A G Herzog
Journal:  Neurology       Date:  1995-09       Impact factor: 9.910

10.  Marriage and fertility in epileptic patients.

Authors:  L V Dansky; E Andermann; F Andermann
Journal:  Epilepsia       Date:  1980-06       Impact factor: 5.864

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