Literature DB >> 23055894

Respiratory syncytial virus: diagnosis, treatment and prevention.

Lea S Eiland1.   

Abstract

Respiratory Syncytial Virus (RSV) is a common virus that infects children and adults; however, children younger than two years of age tend to develop more serious respiratory symptoms. RSV is responsible for thousands of outpatient visits (e.g., emergency room/primary care physician), hospitalizations and can result in death. Treatment is primarily supportive care and the illness resolves without complications in most children. RSV prophylaxis with palivizumab is an option for high-risk infants and children, which can decrease hospitalization and length of stay. Immunocompromised patients are a special population of which ribavirin and palivizumab may be used for treatment. Currently, no medication or vaccine available has been able to show a reduction in mortality from RSV. Future vaccines are in the developmental stage and will hopefully decrease the symptomatic and economic burden of this disease.

Entities:  

Keywords:  child; infant; motavizumab; palivizumab; ribavirin

Year:  2009        PMID: 23055894      PMCID: PMC3461981          DOI: 10.5863/1551-6776-14.2.75

Source DB:  PubMed          Journal:  J Pediatr Pharmacol Ther        ISSN: 1551-6776


  64 in total

1.  The use of albuterol in hospitalized infants with bronchiolitis.

Authors:  J V Dobson; S M Stephens-Groff; S R McMahon; M M Stemmler; S L Brallier; C Bay
Journal:  Pediatrics       Date:  1998-03       Impact factor: 7.124

2.  Effectiveness of ribavirin in otherwise well infants with respiratory syncytial virus-associated respiratory failure. Pediatric Critical Study Group.

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Journal:  J Pediatr       Date:  1996-03       Impact factor: 4.406

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Journal:  Pediatrics       Date:  1997-12       Impact factor: 7.124

4.  Reduction of respiratory syncytial virus hospitalization among premature infants and infants with bronchopulmonary dysplasia using respiratory syncytial virus immune globulin prophylaxis. The PREVENT Study Group.

Authors: 
Journal:  Pediatrics       Date:  1997-01       Impact factor: 7.124

5.  Does ribavirin impact on the hospital course of children with respiratory syncytial virus (RSV) infection? An analysis using the pediatric investigators collaborative network on infections in Canada (PICNIC) RSV database.

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Journal:  Pediatrics       Date:  1997-03       Impact factor: 7.124

6.  Respiratory syncytial virus-related apnea in infants. Demographics and outcome.

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Journal:  Am J Dis Child       Date:  1984-03

7.  Efficacy of albuterol in the management of bronchiolitis.

Authors:  A M Gadomski; R Lichenstein; L Horton; J King; V Keane; T Permutt
Journal:  Pediatrics       Date:  1994-06       Impact factor: 7.124

8.  Prophylactic administration of respiratory syncytial virus immune globulin to high-risk infants and young children. The Respiratory Syncytial Virus Immune Globulin Study Group.

Authors:  J R Groothuis; E A Simoes; M J Levin; C B Hall; C E Long; W J Rodriguez; J Arrobio; H C Meissner; D R Fulton; R C Welliver
Journal:  N Engl J Med       Date:  1993-11-18       Impact factor: 91.245

9.  Role of ECMO in the treatment of respiratory syncytial virus bronchiolitis: a collaborative report.

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Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  1995-09       Impact factor: 5.747

10.  Aerosolized ribavirin in mechanically ventilated children with respiratory syncytial virus lower respiratory tract disease: a prospective, double-blind, randomized trial.

Authors:  K L Meert; A P Sarnaik; M J Gelmini; M W Lieh-Lai
Journal:  Crit Care Med       Date:  1994-04       Impact factor: 7.598

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  19 in total

1.  Prolonged viral replication and longitudinal viral dynamic differences among respiratory syncytial virus infected infants.

Authors:  Monica E Brint; Joshua M Hughes; Aditya Shah; Chelsea R Miller; Lisa G Harrison; Elizabeth A Meals; Jacqueline Blanch; Charlotte R Thompson; Stephania A Cormier; John P DeVincenzo
Journal:  Pediatr Res       Date:  2017-08-09       Impact factor: 3.756

2.  Comparison of Intravenous Palivizumab and Standard of Care for Treatment of Respiratory Syncytial Virus Infection in Mechanically Ventilated Pediatric Patients.

Authors:  Brady J Helmink; Carolyn E Ragsdale; Evan J Peterson; Kathryn G Merkel
Journal:  J Pediatr Pharmacol Ther       Date:  2016 Mar-Apr

3.  Antibiotic therapy versus no antibiotic therapy for children aged 2 to 59 months with WHO-defined non-severe pneumonia and wheeze.

Authors:  Zohra S Lassi; Zahra Ali Padhani; Jai K Das; Rehana A Salam; Zulfiqar A Bhutta
Journal:  Cochrane Database Syst Rev       Date:  2021-01-20

4.  Increase in Detection of Respiratory Syncytial Virus Among Older Adults in Arizona : An Association With Changes in Testing Practices.

Authors:  Rebecca Bridge; Laura M Erhart; Shane Brady; Kenneth Komatsu
Journal:  Public Health Rep       Date:  2021-02-04       Impact factor: 3.117

5.  A multi-laboratory study of diverse RSV neutralization assays indicates feasibility for harmonization with an international standard.

Authors:  Nancy Hosken; Brian Plikaytis; Carrie Trujillo; Kutub Mahmood; Deborah Higgins
Journal:  Vaccine       Date:  2017-05-02       Impact factor: 3.641

6.  In silico analysis of amino acid variation in human respiratory syncytial virus: insights into immunodiagnostics.

Authors:  Claudemir Souza; Nilson It Zanchin; Marco A Krieger; Adriana Ludwig
Journal:  Mem Inst Oswaldo Cruz       Date:  2017-10       Impact factor: 2.743

Review 7.  Cytokines in the Respiratory Airway as Biomarkers of Severity and Prognosis for Respiratory Syncytial Virus Infection: An Update.

Authors:  Yaneisi Vázquez; Liliana González; Loreani Noguera; Pablo A González; Claudia A Riedel; Pablo Bertrand; Susan M Bueno
Journal:  Front Immunol       Date:  2019-06-04       Impact factor: 7.561

8.  Kinetics of Respiratory Syncytial Virus (RSV) Memphis Strain 37 (M37) Infection in the Respiratory Tract of Newborn Lambs as an RSV Infection Model for Human Infants.

Authors:  Alejandro Larios Mora; Laurent Detalle; Albert Van Geelen; Michael S Davis; Thomas Stohr; Jack M Gallup; Mark R Ackermann
Journal:  PLoS One       Date:  2015-12-07       Impact factor: 3.240

9.  Palivizumab Prophylaxis Against Respiratory Syncytial Virus Infection in Children with Immunocompromised Conditions or Down Syndrome: A Multicenter, Post-Marketing Surveillance in Japan.

Authors:  Tomoko Kashiwagi; Yukiko Okada; Ken Nomoto
Journal:  Paediatr Drugs       Date:  2018-02       Impact factor: 3.022

Review 10.  Innate Immune Responses to Highly Pathogenic Coronaviruses and Other Significant Respiratory Viral Infections.

Authors:  Hanaa Ahmed-Hassan; Brianna Sisson; Rajni Kant Shukla; Yasasvi Wijewantha; Nicholas T Funderburg; Zihai Li; Don Hayes; Thorsten Demberg; Namal P M Liyanage
Journal:  Front Immunol       Date:  2020-08-18       Impact factor: 7.561

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