Literature DB >> 23055856

Palatability of liquid anti-infectives: clinician and student perceptions and practice outcomes.

Stacy C Gee1, Tracy M Hagemann.   

Abstract

Oral liquid medications with poor palatability may lead to non-compliance, especially among children. Often, prescribers are not aware of the palatability of the agent that they are prescribing. Eighty-six health-care professionals participated in an open-label taste test of 24 anti-infectives in stock at a pediatric teaching hospital. A sample of the product was placed on a plastic spoon and participants were asked to evaluate their overall impression based on taste, texture, smell, and aftertaste. Participants were then asked to rank the individual products on a visual analog scale. Certain anti-infective formulations were perceived as being much more palatable than others. As a follow-up study, surveys were sent out to assess the impact of the taste test. Participants were asked to evaluate their prescribing and patient counseling habits both before and after the taste test. We found that half of the volunteers had altered their prescribing and/or medication counseling habits as a result of the taste test.

Entities:  

Keywords:  anti-infectives; oral liquid medications; palatability

Year:  2007        PMID: 23055856      PMCID: PMC3462086          DOI: 10.5863/1551-6776-12.4.216

Source DB:  PubMed          Journal:  J Pediatr Pharmacol Ther        ISSN: 1551-6776


  10 in total

1.  Palatability of oral antibiotics among children in an urban primary care center.

Authors:  M L Angelilli; M Toscani; D M Matsui; M J Rieder
Journal:  Arch Pediatr Adolesc Med       Date:  2000-03

2.  Randomized, double blind comparison of brand and generic antibiotic suspensions: II. A study of taste and compliance in children.

Authors:  G M El-Chaar; G Mardy; K Wehlou; L G Rubin
Journal:  Pediatr Infect Dis J       Date:  1996-01       Impact factor: 2.129

3.  Properties of azithromycin that enhance the potential for compliance in children with upper respiratory tract infections.

Authors:  J L Powers
Journal:  Pediatr Infect Dis J       Date:  1996-09       Impact factor: 2.129

4.  Stability of ketoconazole, metolazone, metronidazole, procainamide hydrochloride, and spironolactone in extemporaneously compounded oral liquids.

Authors:  L V Allen; M A Erickson
Journal:  Am J Health Syst Pharm       Date:  1996-09-01       Impact factor: 2.637

5.  Assessment of the palatability of beta-lactamase-resistant antibiotics in children.

Authors:  D Matsui; R Lim; T Tschen; M J Rieder
Journal:  Arch Pediatr Adolesc Med       Date:  1997-06

6.  Antimicrobial drug suspensions: a blind comparison of taste of fourteen common pediatric drugs.

Authors:  M E Ruff; D A Schotik; J W Bass; J M Vincent
Journal:  Pediatr Infect Dis J       Date:  1991-01       Impact factor: 2.129

7.  A double-blind taste comparison of pediatric antibiotic suspensions.

Authors:  R W Steele; B Estrada; R E Begue; A Mirza; D A Travillion; M P Thomas
Journal:  Clin Pediatr (Phila)       Date:  1997-04       Impact factor: 1.168

8.  Prescription medications in infancy and early childhood.

Authors:  P Fosarelli; M Wilson; C DeAngelis
Journal:  Am J Dis Child       Date:  1987-07

9.  Randomized, double blind comparison of brand and generic antibiotic suspensions: I. A study of taste in adults.

Authors:  K M Samulak; G M El-Chaar; L G Rubin
Journal:  Pediatr Infect Dis J       Date:  1996-01       Impact factor: 2.129

10.  Assessment of the palatability of antistaphylococcal antibiotics in pediatric volunteers.

Authors:  D Matsui; A Barron; M J Rieder
Journal:  Ann Pharmacother       Date:  1996-06       Impact factor: 3.154

  10 in total
  7 in total

1.  Community-Associated Methicillin-Resistant Staphylococcus aureus in the Pediatric Population.

Authors:  Carrie W Nemerovski; Kristin C Klein
Journal:  J Pediatr Pharmacol Ther       Date:  2008-10

2.  Instructions for masking the taste of medication for children: Validation of a pictogram tool.

Authors:  Régis Vaillancourt; Yen Truong; Shazya Karmali; Amanda Kraft; Selina Manji; Gilda Villarreal; Annie Pouliot
Journal:  Can Pharm J (Ott)       Date:  2016-10-04

3.  Taste Perceptions of Common Pediatric Antibiotic Suspensions and Associated Prescribing Patterns in Medical Residents.

Authors:  Neelkamal Soares; Rachel Mitchell; Theresa McGoff; Teresa Bailey; Gregory S Wellman
Journal:  J Pediatr Pharmacol Ther       Date:  2022-05-09

Review 4.  Patient-centred pharmaceutical design to improve acceptability of medicines: similarities and differences in paediatric and geriatric populations.

Authors:  Fang Liu; Sejal Ranmal; Hannah K Batchelor; Mine Orlu-Gul; Terry B Ernest; Iwan W Thomas; Talia Flanagan; Catherine Tuleu
Journal:  Drugs       Date:  2014-10       Impact factor: 9.546

5.  Use of Oral Vitamin-D Glass ampoule and tablet: Experience of patients and physicians.

Authors:  Syed Umair Maroof; Faizan Shaukat; Junaid Aslam; Masood Jawaid
Journal:  Pak J Med Sci       Date:  2017 Mar-Apr       Impact factor: 1.088

6.  The Taste of Commercially Available Clarithromycin Oral Pharmaceutical Suspensions in the Palestinian Market: Electronic Tongue and In Vivo Evaluation.

Authors:  Nawaf Abu-Khalaf; Abdel Naser Zaid; Nidal Jaradat; Alaaldin AlKilany; Basima Abu Rumaila; Rowa Al Ramahi; Shrouq Shweiki; Safaa Nidal; Nibal Surakhi
Journal:  Sensors (Basel)       Date:  2018-02-03       Impact factor: 3.576

Review 7.  Extemporaneous Compounding: Selective Pharmacists with Separate Skill.

Authors:  A K Mohiuddin
Journal:  Innov Pharm       Date:  2019-10-31
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.