Literature DB >> 23053668

Widespread over-expression of the non-clustered homeobox gene HLX in acute myeloid leukemia.

Stefan Fröhling.   

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Year:  2012        PMID: 23053668      PMCID: PMC3487543          DOI: 10.3324/haematol.2012.076612

Source DB:  PubMed          Journal:  Haematologica        ISSN: 0390-6078            Impact factor:   9.941


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  6 in total

Review 1.  Hox genes in hematopoiesis and leukemogenesis.

Authors:  B Argiropoulos; R K Humphries
Journal:  Oncogene       Date:  2007-10-15       Impact factor: 9.867

2.  Essential role of Jun family transcription factors in PU.1 knockdown-induced leukemic stem cells.

Authors:  Ulrich Steidl; Frank Rosenbauer; Roel G W Verhaak; Xuesong Gu; Alexander Ebralidze; Hasan H Otu; Steffen Klippel; Christian Steidl; Ingmar Bruns; Daniel B Costa; Katharina Wagner; Manuel Aivado; Guido Kobbe; Peter J M Valk; Emmanuelle Passegué; Towia A Libermann; Ruud Delwel; Daniel G Tenen
Journal:  Nat Genet       Date:  2006-10-15       Impact factor: 38.330

3.  H2.0-like homeobox regulates early hematopoiesis and promotes acute myeloid leukemia.

Authors:  Masahiro Kawahara; Ashley Pandolfi; Boris Bartholdy; Laura Barreyro; Britta Will; Michael Roth; Ujunwa C Okoye-Okafor; Tihomira I Todorova; Maria E Figueroa; Ari Melnick; Constantine S Mitsiades; Ulrich Steidl
Journal:  Cancer Cell       Date:  2012-08-14       Impact factor: 31.743

4.  Prognostic relevance of integrated genetic profiling in acute myeloid leukemia.

Authors:  Jay P Patel; Mithat Gönen; Maria E Figueroa; Hugo Fernandez; Zhuoxin Sun; Janis Racevskis; Pieter Van Vlierberghe; Igor Dolgalev; Sabrena Thomas; Olga Aminova; Kety Huberman; Janice Cheng; Agnes Viale; Nicholas D Socci; Adriana Heguy; Athena Cherry; Gail Vance; Rodney R Higgins; Rhett P Ketterling; Robert E Gallagher; Mark Litzow; Marcel R M van den Brink; Hillard M Lazarus; Jacob M Rowe; Selina Luger; Adolfo Ferrando; Elisabeth Paietta; Martin S Tallman; Ari Melnick; Omar Abdel-Wahab; Ross L Levine
Journal:  N Engl J Med       Date:  2012-03-14       Impact factor: 91.245

5.  Overexpression of CDX2 perturbs HOX gene expression in murine progenitors depending on its N-terminal domain and is closely correlated with deregulated HOX gene expression in human acute myeloid leukemia.

Authors:  Vijay P S Rawat; Silvia Thoene; Vegi M Naidu; Natalia Arseni; Bernhard Heilmeier; Klaus Metzeler; Konstantin Petropoulos; Aniruddha Deshpande; Leticia Quintanilla-Martinez; Stefan K Bohlander; Karsten Spiekermann; Wolfgang Hiddemann; Michaela Feuring-Buske; Christian Buske
Journal:  Blood       Date:  2007-09-12       Impact factor: 22.113

6.  The homeobox gene CDX2 is aberrantly expressed in most cases of acute myeloid leukemia and promotes leukemogenesis.

Authors:  Claudia Scholl; Dimple Bansal; Konstanze Döhner; Karina Eiwen; Brian J P Huntly; Benjamin H Lee; Frank G Rücker; Richard F Schlenk; Lars Bullinger; Hartmut Döhner; D Gary Gilliland; Stefan Fröhling
Journal:  J Clin Invest       Date:  2007-03-08       Impact factor: 14.808

  6 in total
  2 in total

1.  HLX affects cell cycle and proliferation in AML cells via the JAK/STAT signaling pathway.

Authors:  Xia-Yin Zhu; Qun-Yi Guo; Min Zhu; Bao-Guo Chen; Ling-Yan Wang; Dan-Qiong Zhang; Li Zhang; Yan-Ping Shao; Wen-Da Luo
Journal:  Oncol Lett       Date:  2020-06-09       Impact factor: 2.967

2.  A metabolic interplay coordinated by HLX regulates myeloid differentiation and AML through partly overlapping pathways.

Authors:  Indre Piragyte; Thomas Clapes; Aikaterini Polyzou; Ramon I Klein Geltink; Stylianos Lefkopoulos; Na Yin; Pierre Cauchy; Jonathan D Curtis; Lhéanna Klaeylé; Xavier Langa; Cora C A Beckmann; Marcin W Wlodarski; Patrick Müller; Dominic Van Essen; Angelika Rambold; Friedrich G Kapp; Marina Mione; Joerg M Buescher; Erika L Pearce; Alexander Polyzos; Eirini Trompouki
Journal:  Nat Commun       Date:  2018-08-06       Impact factor: 14.919

  2 in total

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