Literature DB >> 23053310

Unexpected malignancies after laparoscopic-assisted supracervical hysterectomies (LASH): an analysis of 1,584 LASH cases.

Juliane U Theben1, Alexander R M Schellong, Christopher Altgassen, Katharina Kelling, Stephanie Schneider, Dietmar Große-Drieling.   

Abstract

OBJECTIVE: The objective of this research was to identify the rate of unexpected malignancies after laparoscopic-assisted supracervical hysterectomies (LASH) and describe the therapy regime.
METHODS: The research is based on a retrospective chart analysis of patients undergoing a simple hysterectomy in the gynecological endoscopy department of a general hospital in Germany.
RESULTS: 2,577 simple hysterectomies conducted between March 2005 and March 2010 were sub-classified in different types of hysterectomies (vaginal-, abdominal-, total-, abdominal supracervical hysterectomy, LAVH, and LASH). This study focuses on the LASH sub-group of 1,584 patients and does not make any comparisons to other operative approaches. Out of the 1,584 patients, 87.8 % (n = 1,391) received preoperative screening to exclude dysplasia or malignancy based on the policy of the German Association for gynecology and obstetrics (DGGG). The screening includes cytology (Pap-smear) and preoperative ultrasound of the uterus or dilatation and curettage (d&c). Unexpected malignancies were found in 0.25 % (n = 4) of the patients pre-screened according to DGGG protocol. Out of the four malign patients, two had endometrial cancer. Two patients had leiomyosarcoma.
CONCLUSION: The study shows that there is a small probability of unexpected malignancies even in correctly pre-screened patients for LASH procedures. Yet in the short-term (28-52 months), malign patients remain recurrence free after treatment. LASH is therefore a good procedure for assumed benign disease.

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Year:  2012        PMID: 23053310     DOI: 10.1007/s00404-012-2559-0

Source DB:  PubMed          Journal:  Arch Gynecol Obstet        ISSN: 0932-0067            Impact factor:   2.344


  20 in total

1.  Prognosis of women with apparent stage I endometrial cancer who had supracervical hysterectomy.

Authors:  Koji Matsuo; Hiroko Machida; Tsuyoshi Takiuchi; Jocelyn Garcia-Sayre; Annie A Yessaian; Lynda D Roman
Journal:  Gynecol Oncol       Date:  2017-02-17       Impact factor: 5.482

2.  Cost-Effectiveness of Laparoscopic Hysterectomy With Morcellation Compared With Abdominal Hysterectomy for Presumed Myomas.

Authors:  Sarah E Rutstein; Matthew T Siedhoff; Elizabeth J Geller; Kemi M Doll; Jennifer M Wu; Daniel L Clarke-Pearson; Stephanie B Wheeler
Journal:  J Minim Invasive Gynecol       Date:  2015-10-22       Impact factor: 4.137

3.  Sentinel node mapping in high risk endometrial cancer after laparoscopic supracervical hysterectomy with morcellation.

Authors:  Alessandro Buda; Cuzzocrea Marco; Carlotta Dolci; Federica Elisei; Romina Baldo; Luca Locatelli; Rodolfo Milani; Cristina Messa
Journal:  Int J Surg Case Rep       Date:  2013-07-16

4.  Characterization and Preoperative Risk Analysis of Leiomyosarcomas at a High-Volume Tertiary Care Center.

Authors:  Ann Peters; Amanda M Sadecky; Daniel G Winger; Richard S Guido; Ted T M Lee; Suketu M Mansuria; Nicole M Donnellan
Journal:  Int J Gynecol Cancer       Date:  2017-07       Impact factor: 3.437

Review 5.  Recurrence of Uterine Smooth Muscle Tumor of Uncertain Malignant Potential: A Systematic Review of the Literature.

Authors:  Jacopo Di Giuseppe; Camilla Grelloni; Lucia Giuliani; Giovanni Delli Carpini; Luca Giannella; Andrea Ciavattini
Journal:  Cancers (Basel)       Date:  2022-05-07       Impact factor: 6.575

6.  Laparoscopic hysterectomy with morcellation vs abdominal hysterectomy for presumed fibroid tumors in premenopausal women: a decision analysis.

Authors:  Matthew T Siedhoff; Stephanie B Wheeler; Sarah E Rutstein; Elizabeth J Geller; Kemi M Doll; Jennifer M Wu; Daniel L Clarke-Pearson
Journal:  Am J Obstet Gynecol       Date:  2015-03-24       Impact factor: 8.661

7.  Incidence of occult leiomyosarcoma in presumed morcellation cases: a database study.

Authors:  Ana M Rodriguez; Mehmet R Asoglu; Muhammet Erdal Sak; Alai Tan; Mostafa A Borahay; Gokhan S Kilic
Journal:  Eur J Obstet Gynecol Reprod Biol       Date:  2015-11-28       Impact factor: 2.831

8.  Malignancy rate of 10,731 uteri morcellated during laparoscopic supracervical hysterectomy (LASH).

Authors:  Bernd Bojahr; Rudy Leon De Wilde; Garri Tchartchian
Journal:  Arch Gynecol Obstet       Date:  2015-03-28       Impact factor: 2.344

9.  Critical analysis of cases of endometrial carcinoma of the uterine corpus incidentally diagnosed after incomplete surgery for other indications. Three case reports and a review of the literature.

Authors:  Małgorzata Gajewska; Mirosław Wielgoś; Grzegorz Panek
Journal:  Prz Menopauzalny       Date:  2014-11-02

Review 10.  The prevalence of occult leiomyosarcoma at surgery for presumed uterine fibroids: a meta-analysis.

Authors:  Elizabeth A Pritts; David J Vanness; Jonathan S Berek; William Parker; Ronald Feinberg; Jacqueline Feinberg; David L Olive
Journal:  Gynecol Surg       Date:  2015-05-19
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