T Yano1, T Nogaki, M Asano, S Tanaka, K Kawakami, Y Matsuda. 1. Matsuda Hospital Colo-proctological Institute, 753 Irinocho, Nishi-ku, Hamamatsu, Shizuoka, 432-8061, Japan. yanotakaaki@hotmail.co.jp
Abstract
PURPOSE: In Japan, a new type of sclerotherapy termed ALTA (aluminum potassium sulfate and tannic acid) injection therapy has recently been introduced. The objectives of this study were to determine whether the presence or absence of antithrombotic treatment (AT) affected the efficacy rate or the occurrence of complications associated with ALTA injection sclerotherapy. METHODS: This study was a case-matched study of 37 patients who underwent ALTA therapy to treat hemorrhoids between 2007 and 2009. Each AT patient was matched for age and degree of hemorrhoids with a control non-AT patient. In each of the subgroups, the therapeutic efficacy of ALTA therapy was evaluated by comparing an assessment completed before therapy with an assessment completed 6 months after therapy. RESULTS: The efficacy in patients with bleeding did not differ between the two groups (P = 0.074). The efficacy in patients with prolapse was significantly lower in the AT group than in the non-AT group (P = 0.013). The two groups did not differ significantly in the occurrence of complications (P = 0.450). CONCLUSIONS: Among patients with hemorrhoids receiving AT, ALTA injection sclerotherapy is recommended for those in whom it is difficult to discontinue AT.
PURPOSE: In Japan, a new type of sclerotherapy termed ALTA (aluminum potassium sulfate and tannic acid) injection therapy has recently been introduced. The objectives of this study were to determine whether the presence or absence of antithrombotic treatment (AT) affected the efficacy rate or the occurrence of complications associated with ALTA injection sclerotherapy. METHODS: This study was a case-matched study of 37 patients who underwent ALTA therapy to treat hemorrhoids between 2007 and 2009. Each AT patient was matched for age and degree of hemorrhoids with a control non-AT patient. In each of the subgroups, the therapeutic efficacy of ALTA therapy was evaluated by comparing an assessment completed before therapy with an assessment completed 6 months after therapy. RESULTS: The efficacy in patients with bleeding did not differ between the two groups (P = 0.074). The efficacy in patients with prolapse was significantly lower in the AT group than in the non-AT group (P = 0.013). The two groups did not differ significantly in the occurrence of complications (P = 0.450). CONCLUSIONS: Among patients with hemorrhoids receiving AT, ALTA injection sclerotherapy is recommended for those in whom it is difficult to discontinue AT.
Authors: Peter Cataldo; C Neal Ellis; Sharon Gregorcyk; Neil Hyman; W Donald Buie; James Church; Jeffrey Cohen; Phillip Fleshner; John Kilkenny; Clifford Ko; David Levien; Richard Nelson; Graham Newstead; Charles Orsay; W Brian Perry; Jan Rakinic; Paul Shellito; Scott Strong; Charles Ternent; Joe Tjandra; Mark Whiteford Journal: Dis Colon Rectum Date: 2005-02 Impact factor: 4.585
Authors: M Takano; J Iwadare; H Ohba; H Takamura; Y Masuda; K Matsuo; T Kanai; H Ieda; Y Hattori; S Kurata; S Koganezawa; K Hamano; S Tsuchiya Journal: Int J Colorectal Dis Date: 2005-04-21 Impact factor: 2.571
Authors: R Scott Nelson; B Mark Ewing; Charles Ternent; Maniamparampil Shashidharan; Garnet J Blatchford; Alan G Thorson Journal: Am J Surg Date: 2008-12 Impact factor: 2.565
Authors: G Cocorullo; R Tutino; N Falco; L Licari; G Orlando; T Fontana; C Raspanti; G Salamone; G Scerrino; G Gallo; M Trompetto; G Gulotta Journal: G Chir Date: 2017 Jan-Feb
Authors: M Trompetto; G Clerico; G F Cocorullo; P Giordano; F Marino; J Martellucci; G Milito; M Mistrangelo; C Ratto Journal: Tech Coloproctol Date: 2015-09-24 Impact factor: 3.781
Authors: Paulo Salgueiro; Ana Célia Caetano; Ana Maria Oliveira; Bruno Rosa; Miguel Mascarenhas-Saraiva; Paula Ministro; Pedro Amaro; Rogério Godinho; Rosa Coelho; Rúben Gaio; Samuel Fernandes; Vítor Fernandes; Fernando Castro-Poças Journal: GE Port J Gastroenterol Date: 2019-09-05
Authors: G Gallo; J Martellucci; A Sturiale; G Clerico; G Milito; F Marino; G Cocorullo; P Giordano; M Mistrangelo; M Trompetto Journal: Tech Coloproctol Date: 2020-01-28 Impact factor: 3.781