Literature DB >> 23051973

Characteristics and treatment course of patients older than 75 years, reaching end-stage renal failure in France. The PSPA study.

Olivier Moranne1, Cecile Couchoud, Cecile Vigneau.   

Abstract

BACKGROUND: The age of patients with end-stage renal disease is increasing in Europe and United States. In France, patients older than 75 years represent 40% of the patients who start renal replacement therapy (dialysis or renal transplantation). In these elderly patients with many comorbidities, the benefit of dialysis remains controversial. To provide clear information to patients about diagnosis, prognosis, and all treatment options, more data are needed on their clinical characteristics, therapeutic projects, and outcome.
METHODS: Researchers present here the ongoing Parcours de Soins des PersonnesAgées (PSPA) multicenter prospective study, which includes 581 patients with a mean age of 82±5 years and an estimated glomerular filtration rate (by sMDRD) of 14±4ml/min/1.73m(2) without dialysis.
RESULTS: Despite a high prevalence of associated comorbidities, most of the patients are autonomous, living at home. Less than 10% are followed jointly by a nephrologist and a geriatrician. At inclusion, postponed dialysis decision due to stable estimated glomerular filtration rate was reported in 43%, 17% of the patients are under evaluation, the decision to start dialysis was chosen in 24% of the patients, nondialysis decision was decided in 16%.
CONCLUSIONS: Geriatricians' expertise may help nephrologists to identify patients at high risk of early death for who nondialysis care may be discussed. They also may be more able to evaluate and anticipate the impact of such restricting treatments. A multidisciplinary approach of these old and frail patients' needs to be reinforced.

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Mesh:

Year:  2012        PMID: 23051973     DOI: 10.1093/gerona/gls162

Source DB:  PubMed          Journal:  J Gerontol A Biol Sci Med Sci        ISSN: 1079-5006            Impact factor:   6.053


  8 in total

1.  Has the yearly increase in the renal replacement therapy population ended?

Authors:  Steven Jay Rosansky; William F Clark
Journal:  J Am Soc Nephrol       Date:  2013-07-18       Impact factor: 10.121

2.  A simple clinical tool to inform the decision-making process to refer elderly incident dialysis patients for kidney transplant evaluation.

Authors:  Emmanuelle Dusseux; Laetitia Albano; Coraline Fafin; Maryvonne Hourmant; Olivier Guérin; Cécile Couchoud; Olivier Moranne
Journal:  Kidney Int       Date:  2015-02-11       Impact factor: 10.612

3.  Development of a risk stratification algorithm to improve patient-centered care and decision making for incident elderly patients with end-stage renal disease.

Authors:  Cécile G Couchoud; Jean-Baptiste R Beuscart; Jean-Claude Aldigier; Philippe J Brunet; Olivier P Moranne
Journal:  Kidney Int       Date:  2015-09-02       Impact factor: 10.612

4.  Supportive Care: Comprehensive Conservative Care in End-Stage Kidney Disease.

Authors:  Fliss E M Murtagh; Aine Burns; Olivier Moranne; Rachael L Morton; Saraladevi Naicker
Journal:  Clin J Am Soc Nephrol       Date:  2016-08-10       Impact factor: 8.237

5.  Competing-risk analysis of death and dialysis initiation among elderly (≥80 years) newly referred to nephrologists: a French prospective study.

Authors:  Bernadette Faller; Jean-Baptiste Beuscart; Luc Frimat
Journal:  BMC Nephrol       Date:  2013-05-07       Impact factor: 2.388

6.  Proceedings From the Symposium on Kidney Disease in Older People: Royal Society of Medicine, London, January 19, 2017.

Authors:  Aza Abdulla; Pandora N Wright; Louise E Ross; Hugh Gallagher; Osasuyi Iyasere; Nan Ma; Carol Bartholomew; Karen Lowton; Edwina A Brown
Journal:  Gerontol Geriatr Med       Date:  2017-12-07

Review 7.  Treatment decisions for older adults with advanced chronic kidney disease.

Authors:  Steven J Rosansky; Jane Schell; Joseph Shega; Jennifer Scherer; Laurie Jacobs; Cecile Couchoud; Deidra Crews; Matthew McNabney
Journal:  BMC Nephrol       Date:  2017-06-19       Impact factor: 2.388

8.  Medication burden and inappropriate prescription risk among elderly with advanced chronic kidney disease.

Authors:  Clarisse Roux-Marson; Jean Baptiste Baranski; Coraline Fafin; Guillaume Exterman; Cecile Vigneau; Cecile Couchoud; Olivier Moranne; P S P A Investigators
Journal:  BMC Geriatr       Date:  2020-03-04       Impact factor: 3.921

  8 in total

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