Literature DB >> 2304611

[A case of hemangioblastoma with subarachnoid dissemination].

T Tohyama1, O Kubo, R Kusano, N Miura, H Himuro.   

Abstract

A case is reported in which a diffuse subarachnoid dissemination occurred after successful removal of a posterior fossa hemangioblastoma. The patient was a 51-year-old man who suffered from headache and gait disturbance, and who was admitted to our hospital on September 25, 1985. Neurological examination revealed trunkal ataxia and increased intracranial pressure. A CT scan with contrast media revealed a high-density lesion with surrounding low-density area in the posterior fossa. Right vertebral angiography demonstrated a round tumor stain behind the medulla oblongata, which was fed by the right posterior inferior cerebellar artery. The complete resection of the tumor was carried out. A biopsy specimen from the tumor showed a picture characteristic of hemangioblastoma. Fourteen months later the patient was readmitted due to the sudden onset of disturbance of consciousness. A CT scan revealed a large intracerebral hematoma in the right putaminal region. Right carotid angiography demonstrated two small tumor stains in the right temporal lobe. An emergency operation to extirpate the hematoma was performed. But the disturbance of consciousness did not improve, and the patient died. At necropsy a lot of small round tumors were recognized at the surface of the bilateral cerebral and cerebellar cortex. They were present in the subarachnoid space and partially invaded the cerebral and cerebellar parenchyma, extending through Virchow-Robin's space. There was no recurrence of the tumor at the site of the original operation. No doubt, a subarachnoid dissemination had occurred. However the histological findings of tumors were similar to the findings recorded in the first biopsy.

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Mesh:

Year:  1990        PMID: 2304611

Source DB:  PubMed          Journal:  No Shinkei Geka        ISSN: 0301-2603


  6 in total

1.  CNS hemangioblastomatosis in a patient without von Hippel-Lindau disease.

Authors:  Arie Franco; Peter Pytel; Rimas V Lukas; Rupa Chennamaneni; John M Collins
Journal:  CNS Oncol       Date:  2017-04

2.  Masked malignant phenotype with a benign appearance: beat-up copy number profile may be the key for hemangioblastoma dissemination.

Authors:  Soichi Oya; Shunsaku Takayanagi; Hirokazu Takami; Masahiro Indo; Takahisa Yamashita; Nobuhito Saito; Toru Matsui
Journal:  Brain Tumor Pathol       Date:  2020-10-18       Impact factor: 3.298

3.  Hemangioblastomatosis of the central nervous system without von Hippel-Lindau disease: a case report.

Authors:  Masayasu Kato; Naoyuki Ohe; Ayumi Okumura; Jun Shinoda; Asuka Nomura; Taro Shuin; Noboru Sakai
Journal:  J Neurooncol       Date:  2005-05       Impact factor: 4.130

4.  Disseminated Hemangioblastoma of the Central Nervous System without Von Hippel-Lindau Disease.

Authors:  Sun-Yoon Chung; Sin-Soo Jeun; Jae-Hyun Park
Journal:  Brain Tumor Res Treat       Date:  2014-10-31

5.  Aggressive dissemination of central nervous system hemangioblastoma without association with von Hippel-Lindau disease: A case report and literature review.

Authors:  François Dantas; Jair Leopoldo Raso; Patrícia Salomé Gouvea Braga; Ricardo Vieira Botelho; Fernando Luiz Rolemberg Dantas
Journal:  Surg Neurol Int       Date:  2022-08-12

6.  Disseminated hemangioblastomatosis of the central nervous system without von Hippel-Lindau disease: a case report.

Authors:  Hong-Rae Kim; Yeon-Lim Suh; Jong-Won Kim; Jung-Il Lee
Journal:  J Korean Med Sci       Date:  2009-07-30       Impact factor: 2.153

  6 in total

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