| Literature DB >> 23044866 |
Jakub Simeček1, Hans-Jürgen Wester, Johannes Notni.
Abstract
The 1,4,7-triazacyclononane-1,4,7-tris(methylenephosphinic acid) chelators TRAP and NOPO are complexing copper-64 with similar efficiency as 1,4,7-triazacyclononane-triacetic acid (NOTA). The kinetic stability of Cu-64-labelled TRAP-peptides is sufficient for PET imaging at early time points (1-2 h post injection). For labelling of TRAP conjugates, Cu-64 can be recommended as an alternative to Ga-68 to achieve higher resolution of PET images.Entities:
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Year: 2012 PMID: 23044866 DOI: 10.1039/c2dt31880f
Source DB: PubMed Journal: Dalton Trans ISSN: 1477-9226 Impact factor: 4.390