Literature DB >> 23044407

Development of new generation influenza vaccines: recipes for success?

E S Pronker1, E Claassen, A D M E Osterhaus.   

Abstract

As infectious diseases cause approximately 25% of the annual global mortality, vaccines are found to be a time proven and promising response to infectious disease need. However, like for pharmaceutical small molecules, vaccine development is lengthy, risky and resource demanding. Faced with an attrition rate estimated around 80%, key opinion leaders were interviewed with the question: is there a recipe for success?
Copyright © 2012 Elsevier Ltd. All rights reserved.

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Year:  2012        PMID: 23044407     DOI: 10.1016/j.vaccine.2012.09.071

Source DB:  PubMed          Journal:  Vaccine        ISSN: 0264-410X            Impact factor:   3.641


  6 in total

1.  Temperature-Sensitive Live-Attenuated Canine Influenza Virus H3N8 Vaccine.

Authors:  Aitor Nogales; Laura Rodriguez; Caroline Chauché; Kai Huang; Emma C Reilly; David J Topham; Pablo R Murcia; Colin R Parrish; Luis Martínez-Sobrido
Journal:  J Virol       Date:  2017-01-31       Impact factor: 5.103

2.  Downregulating viral gene expression: codon usage bias manipulation for the generation of novel influenza A virus vaccines.

Authors:  Steven F Baker; Aitor Nogales; Luis Martínez-Sobrido
Journal:  Future Virol       Date:  2015-06       Impact factor: 1.831

Review 3.  Reverse Genetics Approaches for the Development of Influenza Vaccines.

Authors:  Aitor Nogales; Luis Martínez-Sobrido
Journal:  Int J Mol Sci       Date:  2016-12-22       Impact factor: 5.923

Review 4.  Temperature Sensitive Mutations in Influenza A Viral Ribonucleoprotein Complex Responsible for the Attenuation of the Live Attenuated Influenza Vaccine.

Authors:  Luis Martínez-Sobrido; Olve Peersen; Aitor Nogales
Journal:  Viruses       Date:  2018-10-15       Impact factor: 5.048

Review 5.  Novel Approaches for The Development of Live Attenuated Influenza Vaccines.

Authors:  Pilar Blanco-Lobo; Aitor Nogales; Laura Rodríguez; Luis Martínez-Sobrido
Journal:  Viruses       Date:  2019-02-22       Impact factor: 5.048

6.  Risk in vaccine research and development quantified.

Authors:  Esther S Pronker; Tamar C Weenen; Harry Commandeur; Eric H J H M Claassen; Albertus D M E Osterhaus
Journal:  PLoS One       Date:  2013-03-20       Impact factor: 3.240

  6 in total

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