Literature DB >> 23043476

Exploring bioactive peptides from natural sources for oxytocin and vasopressin drug discovery.

Christian W Gruber1, Markus Muttenthaler2, Johannes Koehbach3.   

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Year:  2012        PMID： 23043476      PMCID： PMC3816348          DOI： 10.4155/fmc.12.108

Source DB:  PubMed          Journal:  Future Med Chem        ISSN： 1756-8919            Impact factor:   3.808


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  23 in total

Review 1.  The oxytocin receptor system: structure, function, and regulation.

Authors:  G Gimpl; F Fahrenholz
Journal:  Physiol Rev       Date:  2001-04       Impact factor: 37.312

Review 2.  Chemical modifications designed to improve peptide stability: incorporation of non-natural amino acids, pseudo-peptide bonds, and cyclization.

Authors:  Luca Gentilucci; Rossella De Marco; Lucia Cerisoli
Journal:  Curr Pharm Des       Date:  2010       Impact factor: 3.116

3.  New, potent, selective, and short-acting peptidic V1a receptor agonists.

Authors:  Kazimierz Wisniewski; Robert Galyean; Hiroe Tariga; Sudarkodi Alagarsamy; Glenn Croston; Joshua Heitzmann; Arash Kohan; Halina Wisniewska; Régent Laporte; Pierre J-M Rivière; Claudio D Schteingart
Journal:  J Med Chem       Date:  2011-06-20       Impact factor: 7.446

Review 4.  The vasopressin system: physiology and clinical strategies.

Authors:  Tanja A Treschan; Jürgen Peters
Journal:  Anesthesiology       Date:  2006-09       Impact factor: 7.892

Review 5.  Ligand-based peptide design and combinatorial peptide libraries to target G protein-coupled receptors.

Authors:  Christian W Gruber; Markus Muttenthaler; Michael Freissmuth
Journal:  Curr Pharm Des       Date:  2010       Impact factor: 3.116

6.  Oxytocin increases trust in humans.

Authors:  Michael Kosfeld; Markus Heinrichs; Paul J Zak; Urs Fischbacher; Ernst Fehr
Journal:  Nature       Date:  2005-06-02       Impact factor: 49.962

7.  Modulating oxytocin activity and plasma stability by disulfide bond engineering.

Authors:  Markus Muttenthaler; Asa Andersson; Aline D de Araujo; Zoltan Dekan; Richard J Lewis; Paul F Alewood
Journal:  J Med Chem       Date:  2010-11-30       Impact factor: 7.446

Review 8.  Oxytocin, vasopressin, and the neurogenetics of sociality.

Authors:  Zoe R Donaldson; Larry J Young
Journal:  Science       Date:  2008-11-07       Impact factor: 47.728

9.  Discovery of defense- and neuropeptides in social ants by genome-mining.

Authors:  Christian W Gruber; Markus Muttenthaler
Journal:  PLoS One       Date:  2012-03-20       Impact factor: 3.240

10.  Characterization of the neurohypophysial hormone gene loci in elephant shark and the Japanese lamprey: origin of the vertebrate neurohypophysial hormone genes.

Authors:  Pai-Chung Gwee; Boon-Hui Tay; Sydney Brenner; Byrappa Venkatesh
Journal:  BMC Evol Biol       Date:  2009-02-26       Impact factor: 3.260
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  26 in total

Review 1.  Oxytocin/vasopressin-like neuropeptide signaling in insects.

Authors:  Edin Muratspahić; Emilie Monjon; Leopold Duerrauer; Stephen M Rogers; Darron A Cullen; Jozef Vanden Broeck; Christian W Gruber
Journal:  Vitam Horm       Date:  2019-10-18       Impact factor: 3.421

2.  [MUW resarcher of the month].

Authors:  Johannes Koehbach
Journal:  Wien Klin Wochenschr       Date:  2014-09       Impact factor: 1.704

3.  Binding Characteristics of Two Oxytocin Variants and Vasopressin at Oxytocin Receptors from Four Primate Species with Different Social Behavior Patterns.

Authors:  Jack H Taylor; Nancy A Schulte; Jeffrey A French; Myron L Toews
Journal:  J Pharmacol Exp Ther       Date:  2018-08-01       Impact factor: 4.030

4.  Toxin-like neuropeptides in the sea anemone Nematostella unravel recruitment from the nervous system to venom.

Authors:  Maria Y Sachkova; Morani Landau; Joachim M Surm; Jason Macrander; Shir A Singer; Adam M Reitzel; Yehu Moran
Journal:  Proc Natl Acad Sci U S A       Date:  2020-10-15       Impact factor: 11.205

Review 5.  Peptidomimetic therapeutics: scientific approaches and opportunities.

Authors:  Nir Qvit; Samuel J S Rubin; Travis J Urban; Daria Mochly-Rosen; Eric R Gross
Journal:  Drug Discov Today       Date:  2016-11-14       Impact factor: 7.851

Review 6.  Oxytocin structure and function in New World monkeys: from pharmacology to behavior.

Authors:  Aaryn Mustoe; Jack H Taylor; Jeffrey A French
Journal:  Integr Zool       Date:  2018-11       Impact factor: 2.654

7.  From ethnopharmacology to drug design.

Authors:  Johannes Koehbach; Christian W Gruber
Journal:  Commun Integr Biol       Date:  2014-01-08

Review 8.  Neuropeptide diversity and the regulation of social behavior in New World primates.

Authors:  Jeffrey A French; Jack H Taylor; Aaryn C Mustoe; Jon Cavanaugh
Journal:  Front Neuroendocrinol       Date:  2016-03-25       Impact factor: 8.606

9.  Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species.

Authors:  Markus Muttenthaler; Åsa Andersson; Irina Vetter; Rohit Menon; Marta Busnelli; Lotten Ragnarsson; Christian Bergmayr; Sarah Arrowsmith; Jennifer R Deuis; Han Sheng Chiu; Nathan J Palpant; Margaret O'Brien; Terry J Smith; Susan Wray; Inga D Neumann; Christian W Gruber; Richard J Lewis; Paul F Alewood
Journal:  Sci Signal       Date:  2017-12-05       Impact factor: 8.192

10.  Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design.

Authors:  Johannes Koehbach; Margaret O'Brien; Markus Muttenthaler; Marion Miazzo; Muharrem Akcan; Alysha G Elliott; Norelle L Daly; Peta J Harvey; Sarah Arrowsmith; Sunithi Gunasekera; Terry J Smith; Susan Wray; Ulf Göransson; Philip E Dawson; David J Craik; Michael Freissmuth; Christian W Gruber
Journal:  Proc Natl Acad Sci U S A       Date:  2013-11-18       Impact factor: 11.205
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