| Literature DB >> 23043174 |
Feng Chen1, Jiajia Liu, Zhuanqiang Yan, Di Liu, Jun Ji, Jianping Qin, Haiyan Li, Jingyun Ma, Yingzuo Bi, Qingmei Xie.
Abstract
A novel isolate of infectious bursal disease virus (IBDV) was designated GX-NN-L. The GX-NN-L IBDV was a very virulent infectious bursal disease virus (vvIBDV) isolated from broiler flocks in Guangxi province, China, in 2011. The GX-NN-L IBDV caused high mortality, immunosuppression, low weight gain, and bursal atrophy in commercial broilers. Here, we report the complete genome sequence of the GX-NN-L IBDV, a reassortment strain with segments A and B derived from very virulent strains and attenuated IBDV, respectively. These findings from this study provide additional insights into the genetic exchange between attenuated and very virulent strains of IBDV and continuous monitoring of the spread of the virus in chicken.Entities:
Mesh：
Substances：
Year: 2012 PMID： 23043174 PMCID： PMC3486314 DOI： 10.1128/JVI.02043-12
Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103