| Literature DB >> 23042588 |
Yelena Y Janjigian1, David P Kelsen.
Abstract
Gastric cancer is among the most common human malignancies and the second leading cause of cancer-related death. The different epidemiologic and histopathology of subtypes of gastric cancer are associated with different genomic patterns. Data suggests that gene expression patterns of proximal, distal gastric cancers-intestinal type, and diffuse/signet cell are well separated. This review summarizes the genetic and epigenetic changes thought to drive gastric cancer and the emerging paradigm of gastric cancer as three unique disease subtypes.Entities:
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Year: 2012 PMID: 23042588 DOI: 10.1002/jso.23263
Source DB: PubMed Journal: J Surg Oncol ISSN: 0022-4790 Impact factor: 3.454