Literature DB >> 23042013

Cytomegalovirus Retinitis in an ALL child on exclusive chemotherapy treated successfully with intravitreal ganciclovir alone.

Ramandeep Singh1, Rishiraj Singh, Amita Trehan, Richa Jain, Swapnil Bhalekar.   

Abstract

A child suffering from acute lymphoblastic leukemia on treatment with exclusive chemotherapy presented with vision-threatening cytomegalovirus (CMV) retinitis in 1 eye. Prompt diagnosis and treatment with 3 weekly doses of 2 mg/0.1 mL intravitreal ganciclovir resulted in successful healing of CMV retinitis with restoration of visual acuity. In children with acute lymphoblastic leukemia on exclusive chemotherapy without hematopoietic stem cell transplantation, CMV retinitis has been reported in only 1 case in literature. This child was treated successfully with intravenous ganciclovir. This report highlights the use of successful intravitreal ganciclovir in pediatric age group to avoid side effects of systemic ganciclovir.

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Year:  2013        PMID： 23042013     DOI： 10.1097/MPH.0b013e31827078ad

Source DB:  PubMed          Journal:  J Pediatr Hematol Oncol        ISSN： 1077-4114            Impact factor:   1.289


  7 in total

1.  An Interesting Case of CMV Retinitis in a Case of ALL on Maintenance Therapy.

Authors:  Pawan Kumar Singh; Aniruddha Purushottam Dayama; Rakhi Maiwall; Vineet Sehgal; Pradeep Venkatesh; Pravas Chandra Mishra; Tulika Seth; Manoranjan Mahapatra
Journal:  Indian J Hematol Blood Transfus       Date:  2013-12-06       Impact factor: 0.900

2.  Outcome of cytomegalovirus retinitis in immunocompromised patients without Human Immunodeficiency Virus treated with intravitreal ganciclovir injection.

Authors:  Aniruddha Agarwal; Neha Kumari; Amita Trehan; Alka Khadwal; Mangat R Dogra; Vishali Gupta; Aman Sharma; Amod Gupta; Ramandeep Singh
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2014-02-21       Impact factor: 3.117

3.  Initial intravitreal injection of high-dose ganciclovir for cytomegalovirus retinitis in HIV-negative patients.

Authors:  Zhuyun Qian; Haili Li; Yong Tao; Wensheng Li
Journal:  BMC Ophthalmol       Date:  2018-12-10       Impact factor: 2.209

4.  Unilateral Cytomegalovirus Retinitis in a Child With Acute Lymphoblastic Leukemia While on Maintenance Chemotherapy.

Authors:  Rahaf A Mandura; Karim Talat; Wasil Jastaniah
Journal:  Cureus       Date:  2021-05-26

5.  Cytomegalovirus Retinitis in an ALL Child during Maintenance Therapy Treated Successfully with Intravenous Ganciclovir.

Authors:  Hande Celiker; Ayse Karaaslan; Eda Kepenekli Kadayifci; Serkan Atici; Ahmet Soysal; Haluk Kazokoglu; Ahmet Koc
Journal:  Case Rep Ophthalmol Med       Date:  2014-08-03

6.  Good syndrome and other causes of cytomegalovirus retinitis in HIV-negative patients-case report and comprehensive review of the literature.

Authors:  Kenneth M Downes; Dariusz Tarasewicz; Laurie J Weisberg; Emmett T Cunningham
Journal:  J Ophthalmic Inflamm Infect       Date:  2016-01-25

7.  Monitoring of cytomegalovirus infection in non-transplant pediatric acute lymphoblastic leukemia patients during chemotherapy.

Authors:  Nonthapan Phasuk; Jiraporn Keatkla; Sasivimol Rattanasiri; Chonnamet Techasaensiri; Usanarat Anurathapan; Nopporn Apiwattanakul
Journal:  Medicine (Baltimore)       Date:  2019-01       Impact factor: 1.817
  7 in total

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