Literature DB >> 23040489

Clinical impact of switching conventional enzyme immunoassay with nucleic acid amplification test for suspected Clostridium difficile-associated diarrhea.

Steven W Johnson1, Meganne Kanatani, Romney M Humphries, Daniel Z Uslan.   

Abstract

The impact of a new Clostridium difficile nucleic acid amplification test (NAAT) on antibiotic utilization in patients with suspected C difficile infection was assessed. This single-center, cross-sectional study of 270 patients demonstrated that the use of NAAT decreased antibiotic expenditure by reducing prolonged empiric days of therapy in these patients.
Copyright © 2013 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Mosby, Inc. All rights reserved.

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Year:  2012        PMID： 23040489     DOI： 10.1016/j.ajic.2012.04.329

Source DB:  PubMed          Journal:  Am J Infect Control        ISSN： 0196-6553            Impact factor:   2.918


  2 in total

1.  Performance of Clostridium difficile toxin enzyme immunoassay and nucleic acid amplification tests stratified by patient disease severity.

Authors:  Romney M Humphries; Daniel Z Uslan; Zachary Rubin
Journal:  J Clin Microbiol       Date:  2012-12-26       Impact factor: 5.948

2.  Effect of nucleic acid amplification testing on population-based incidence rates of Clostridium difficile infection.

Authors:  Carolyn V Gould; Jonathan R Edwards; Jessica Cohen; Wendy M Bamberg; Leigh Ann Clark; Monica M Farley; Helen Johnston; Joelle Nadle; Lisa Winston; Dale N Gerding; L Clifford McDonald; Fernanda C Lessa
Journal:  Clin Infect Dis       Date:  2013-07-29       Impact factor: 20.999
  2 in total

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