OBJECTIVE: To determine the burden of maternal morbidity in early pregnancy in rural northern Bangladesh. METHODS: A cross-sectional analysis was performed on baseline morbidity data from 42 896 pregnant women enrolled in a vitamin A supplementation trial. One-week histories for 31 defined symptoms were collected at 5-12 weeks of gestation. Ten illnesses were defined, compatible with ICD-10 diagnoses and WHO definitions. Prevalence, duration, and treatment-seeking behaviors were determined for each symptom and illness. Risk of wasting malnutrition was compared between symptomatic and asymptomatic women. RESULTS: In total, 93.1% of women reported at least 1 symptom. The most frequent symptoms were poor appetite (53.3%), vaginal discharge (48.7%), and nausea (48.1%), each of which lasted 22-27 days. The most prevalent illnesses were anemia (36.4%), morning sickness (17.2%), excessive vomiting (7.0%), and reproductive tract infections (6.7%). Symptoms that prompted treatment seeking included jaundice, high-grade fever, and swelling of hands and face. Odds ratios for malnutrition were higher among women with symptoms of anemia (1.30; 95% confidence interval [CI], 1.24-1.36), vaginal discharge (1.37; 95% CI, 1.31-1.43), and high-grade fever (1.23; 95% CI, 1.10-1.37) than among those without symptoms. CONCLUSION: Women in rural Bangladesh report substantial morbidity in the first trimester.
OBJECTIVE: To determine the burden of maternal morbidity in early pregnancy in rural northern Bangladesh. METHODS: A cross-sectional analysis was performed on baseline morbidity data from 42 896 pregnant women enrolled in a vitamin A supplementation trial. One-week histories for 31 defined symptoms were collected at 5-12 weeks of gestation. Ten illnesses were defined, compatible with ICD-10 diagnoses and WHO definitions. Prevalence, duration, and treatment-seeking behaviors were determined for each symptom and illness. Risk of wasting malnutrition was compared between symptomatic and asymptomatic women. RESULTS: In total, 93.1% of women reported at least 1 symptom. The most frequent symptoms were poor appetite (53.3%), vaginal discharge (48.7%), and nausea (48.1%), each of which lasted 22-27 days. The most prevalent illnesses were anemia (36.4%), morning sickness (17.2%), excessive vomiting (7.0%), and reproductive tract infections (6.7%). Symptoms that prompted treatment seeking included jaundice, high-grade fever, and swelling of hands and face. Odds ratios for malnutrition were higher among women with symptoms of anemia (1.30; 95% confidence interval [CI], 1.24-1.36), vaginal discharge (1.37; 95% CI, 1.31-1.43), and high-grade fever (1.23; 95% CI, 1.10-1.37) than among those without symptoms. CONCLUSION:Women in rural Bangladesh report substantial morbidity in the first trimester.
Authors: Nicholas J Kassebaum; Rashmi Jasrasaria; Mohsen Naghavi; Sarah K Wulf; Nicole Johns; Rafael Lozano; Mathilda Regan; David Weatherall; David P Chou; Thomas P Eisele; Seth R Flaxman; Rachel L Pullan; Simon J Brooker; Christopher J L Murray Journal: Blood Date: 2013-12-02 Impact factor: 22.113
Authors: Amanda Regodón Wallin; James M Tielsch; Subarna K Khatry; Luke C Mullany; Janet A Englund; Helen Chu; Steven C LeClerq; Joanne Katz Journal: BMC Pregnancy Childbirth Date: 2020-09-17 Impact factor: 3.007
Authors: Shegufta S Sikder; Alain B Labrique; Abu A Shamim; Hasmot Ali; Sucheta Mehra; Lee Wu; Saijuddin Shaikh; Keith P West; Parul Christian Journal: BMC Pregnancy Childbirth Date: 2014-10-04 Impact factor: 3.007
Authors: Jinhee Hur; Keith P West; Abu Ahmed Shamim; Mahbubur Rashid; Alain B Labrique; Lee S F Wu; Hasmot Ali; Barkat Ullah; Kerry J Schulze; Rolf D W Klemm; Parul Christian Journal: Matern Child Nutr Date: 2020-03-24 Impact factor: 3.092