BACKGROUND: Our aim was to determine functional outcome of very preterm-born and small-for-gestational-age (SGA) children as compared with matched controls at school age. METHODS: We included 28 very preterm SGA children (GA <32 wk, birth weight (BW) <10th percentile), born in 2000-2001. We also included 28 very preterm but appropriate-for-gestational-age (AGA) children, matched for GA, gender, and birth year, as controls. We assessed motor skills, intelligence quotient (IQ), attention, verbal memory, visual perception, visuomotor integration, executive functioning, and behavior of both sets of children at school age. RESULTS: The SGA children had a median GA of 29.7 wk and BW of 888 g, whereas the controls had a median GA of 29.4 wk and BW of 1,163 g. At 8.6 y, the median total IQ of the SGA children was 94 as compared with 95 in the controls (not significant). Performance IQ was significantly lower in SGA children (89 vs. 95, P = 0.043), whereas verbal IQ was not (95 vs. 95). Total motor skills (P = 0.048) and fine motor skills (P = 0.021) were worse in SGA children. Furthermore, SGA children scored lower on selective attention (P = 0.026) and visual perception (P = 0.025). Other scores did not differ significantly between groups. CONCLUSION: The differences we found between the groups were small. This suggests that the impaired functioning of very preterm-born SGA children is attributable to their having been born very preterm rather than to being SGA.
BACKGROUND: Our aim was to determine functional outcome of very preterm-born and small-for-gestational-age (SGA) children as compared with matched controls at school age. METHODS: We included 28 very preterm SGA children (GA <32 wk, birth weight (BW) <10th percentile), born in 2000-2001. We also included 28 very preterm but appropriate-for-gestational-age (AGA) children, matched for GA, gender, and birth year, as controls. We assessed motor skills, intelligence quotient (IQ), attention, verbal memory, visual perception, visuomotor integration, executive functioning, and behavior of both sets of children at school age. RESULTS: The SGA children had a median GA of 29.7 wk and BW of 888 g, whereas the controls had a median GA of 29.4 wk and BW of 1,163 g. At 8.6 y, the median total IQ of the SGA children was 94 as compared with 95 in the controls (not significant). Performance IQ was significantly lower in SGA children (89 vs. 95, P = 0.043), whereas verbal IQ was not (95 vs. 95). Total motor skills (P = 0.048) and fine motor skills (P = 0.021) were worse in SGA children. Furthermore, SGA children scored lower on selective attention (P = 0.026) and visual perception (P = 0.025). Other scores did not differ significantly between groups. CONCLUSION: The differences we found between the groups were small. This suggests that the impaired functioning of very preterm-born SGA children is attributable to their having been born very preterm rather than to being SGA.
Authors: Kelly K Ferguson; Sara Sammallahti; Emma Rosen; Michiel van den Dries; Anjoeka Pronk; Suzanne Spaan; Mònica Guxens; Henning Tiemeier; Romy Gaillard; Vincent W V Jaddoe Journal: Epidemiology Date: 2021-09-01 Impact factor: 4.860
Authors: Amanda L Smith; Courtney A Hill; Michelle Alexander; Caitlin E Szalkowski; James J Chrobak; Ted S Rosenkrantz; R Holly Fitch Journal: Brain Sci Date: 2014-04-02
Authors: Ayesha Sania; Christopher R Sudfeld; Goodarz Danaei; Günther Fink; Dana C McCoy; Zhaozhong Zhu; Mary C Smith Fawzi; Mehmet Akman; Shams E Arifeen; Aluisio J D Barros; David Bellinger; Maureen M Black; Alemtsehay Bogale; Joseph M Braun; Nynke van den Broek; Verena Carrara; Paulita Duazo; Christopher Duggan; Lia C H Fernald; Melissa Gladstone; Jena Hamadani; Alexis J Handal; Siobán Harlow; Melissa Hidrobo; Chris Kuzawa; Ingrid Kvestad; Lindsey Locks; Karim Manji; Honorati Masanja; Alicia Matijasevich; Christine McDonald; Rose McGready; Arjumand Rizvi; Darci Santos; Leticia Santos; Dilsad Save; Roger Shapiro; Barbara Stoecker; Tor A Strand; Sunita Taneja; Martha-Maria Tellez-Rojo; Fahmida Tofail; Aisha K Yousafzai; Majid Ezzati; Wafaie Fawzi Journal: BMJ Open Date: 2019-10-03 Impact factor: 2.692