Literature DB >> 23037652

Hyperammonemia associated with valproic acid use in elderly psychiatric patients.

Suzanne Holroyd1, Jeffrey T Overdyke.   

Abstract

Valproic acid (VPA) is associated with hyperammonemia; however, little is known about this phenomenon in the geriatric psychiatric population. Of 12 such patients prescribed VPA, 83.3% had elevated ammonia. This occurred in the absence of elevated liver enzymes, and there was no association of VPA serum-level to hyperammonemia.

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Year:  2012        PMID: 23037652     DOI: 10.1176/appi.neuropsych.10100151

Source DB:  PubMed          Journal:  J Neuropsychiatry Clin Neurosci        ISSN: 0895-0172            Impact factor:   2.198


  4 in total

1.  Valproate-Related Hyperammonemia in Older Adult Psychiatric Inpatients.

Authors:  Lawrence W Adler; William T Regenold
Journal:  Prim Care Companion CNS Disord       Date:  2015-04-02

2.  Association between the blood concentrations of ammonia and carnitine/amino acid of schizophrenic patients treated with valproic acid.

Authors:  Masazumi Ando; Hideaki Amayasu; Takahiro Itai; Hisahiro Yoshida
Journal:  Biopsychosoc Med       Date:  2017-07-05

3.  Risk factors of hyperammonemia in patients with epilepsy under valproic acid therapy.

Authors:  Yu-Lung Tseng; Chi-Ren Huang; Chih-Hsiang Lin; Yan-Ting Lu; Cheng-Hsien Lu; Nai-Ching Chen; Chiung-Chih Chang; Wen-Neng Chang; Yao-Chung Chuang
Journal:  Medicine (Baltimore)       Date:  2014-09       Impact factor: 1.889

4.  Valproic Acid Induced Hyperammonemia in a Long Time Treated Patient.

Authors:  Rohit Aiyer; Margaret Seide; Robert G Stern
Journal:  Case Rep Psychiatry       Date:  2016-07-19
  4 in total

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