| Literature DB >> 23036796 |
Dean Edwards1, Eli Boritz, Edward W Cowen, Ronald S Brown.
Abstract
BACKGROUND: The growth in the use of anti-tumor necrosis factor α (TNF-α) agents for treatment of inflammatory conditions has led to increased recognition of the side effects associated with this class of drugs. CASE DESCRIPTION: We report a case of a patient who developed erythema multiforme (EM) major with characteristic oral and cutaneous lesions following treatment with the anti-TNF-α medication infliximab therapy for Crohn's disease (CD). CLINICAL IMPLICATIONS: To our knowledge, this is the first reported case of infliximab-induced EM secondary to the treatment of CD. It is important for dental clinicians evaluating patients using anti-TNF-α agents to be aware of this possible complication. Published by Mosby, Inc.Entities:
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Year: 2012 PMID： 23036796 PMCID： PMC3540144 DOI： 10.1016/j.oooo.2012.08.001
Source DB: PubMed Journal: Oral Surg Oral Med Oral Pathol Oral Radiol