Literature DB >> 23035626

The direct and indirect costs of long bone fractures in a working age US population.

Machaon Bonafede1, Derek Espindle, Anthony G Bower.   

Abstract

OBJECTIVE: Information regarding the burden of fractures is limited, especially among working age patients. The objective of this study was to evaluate the direct and indirect costs associated with long bone fractures in a working age population using real-world claims data.
METHODS: This was a claims-based retrospective analysis, comparing adult patients in the 6 months before and 6 months after a long bone fracture between 1/1/2001 and 12/31/2008 using the MarketScan Research Databases. Outcomes included direct medical costs and utilization, as well as work absenteeism and short term disability, which was available for a sub-set of the patients. Observed and adjusted incremental costs (i.e., the difference in costs before and after a fracture) were evaluated and reported in 2008 US$.
RESULTS: A total of 208,094 patients with at least one fracture were included in the study. Six, mutually exclusive fracture cohorts were evaluated: tibia shaft (n = 49,839), radius (n = 97,585), hip (n = 11,585), femur (n = 6788), humerus (n = 29,884), and those with multiple long bone fractures (n = 12,413). Average unadjusted direct costs in the 6-months before a long bone fracture ranged from $3291 (radius) to $12,923 (hip). The average incremental direct cost increase in the 6-months following a fracture ranged from $5707 (radius) to $39,041 (multiple fractures). Incremental absenteeism costs ranged from $950 (radius) to $2600 (multiple fractures), while incremental short-term disability costs ranged from $2050 (radius) to $4600 (multiple fractures).
CONCLUSIONS: The results of this study indicate that long bone fractures are costly, both in terms of direct medical costs and lost productivity. Workplace absences and short-term disability represent a significant component of the burden of long bone fractures. These results may not be generalizable to all patients with fractures in the US, and do not reflect the burden of undiagnosed or sub-clinical fractures.

Entities:  

Mesh:

Year:  2012        PMID: 23035626     DOI: 10.3111/13696998.2012.737391

Source DB:  PubMed          Journal:  J Med Econ        ISSN: 1369-6998            Impact factor:   2.448


  24 in total

1.  Injectable porcine bone demineralized and digested extracellular matrix-PEGDA hydrogel blend for bone regeneration.

Authors:  Fabian Obregon-Miano; Ali Fathi; Catherine Rathsam; Isbel Sandoval; Fariba Deheghani; Axel Spahr
Journal:  J Mater Sci Mater Med       Date:  2020-01-27       Impact factor: 3.896

2.  Tibial shaft fracture: A large-scale study defining the injured population and associated injuries.

Authors:  Nidharshan S Anandasivam; Glenn S Russo; Matthew S Swallow; Bryce A Basques; Andre M Samuel; Nathaniel T Ondeck; Sophie H Chung; Jennifer M Fischer; Daniel D Bohl; Jonathan N Grauer
Journal:  J Clin Orthop Trauma       Date:  2017-07-24

3.  Healing, nonunion, and re-operation after internal fixation of diaphyseal and distal femoral fractures: a systematic review and meta-analysis.

Authors:  Riikka E Koso; Cristina Terhoeve; R Grant Steen; Robert Zura
Journal:  Int Orthop       Date:  2018-03-08       Impact factor: 3.075

4.  Baicalin augments the differentiation of osteoblasts via enhancement of microRNA-217.

Authors:  Qi Wang; Donglei Shi; Yuanyuan Geng; Qishan Huang; Longzhan Xiang
Journal:  Mol Cell Biochem       Date:  2019-10-12       Impact factor: 3.396

5.  Blood Flow Restriction Therapy after Closed Treatment of Distal Radius Fractures.

Authors:  Jill M Cancio; Nicole M Sgromolo; Peter C Rhee
Journal:  J Wrist Surg       Date:  2019-04-16

6.  The burden of osteoporotic hip fractures in Portugal: costs, health related quality of life and mortality.

Authors:  A Marques; Ó Lourenço; J A P da Silva
Journal:  Osteoporos Int       Date:  2015-05-19       Impact factor: 4.507

7.  VEGFA From Early Osteoblast Lineage Cells (Osterix+) Is Required in Mice for Fracture Healing.

Authors:  Evan G Buettmann; Jennifer A McKenzie; Nicole Migotsky; David Aw Sykes; Pei Hu; Susumu Yoneda; Matthew J Silva
Journal:  J Bone Miner Res       Date:  2019-08-01       Impact factor: 6.741

8.  Bone marrow aspirate concentrate/platelet-rich fibrin augmentation accelerates healing of aseptic upper limb nonunions.

Authors:  Alessandro Mazzotta; Cesare Stagni; Martina Rocchi; Nicola Rani; Nicolandrea Del Piccolo; Giuseppe Filardo; Dante Dallari
Journal:  J Orthop Traumatol       Date:  2021-06-05

Review 9.  Recent Advances and Future of Gene Therapy for Bone Regeneration.

Authors:  Galina Shapiro; Raphael Lieber; Dan Gazit; Gadi Pelled
Journal:  Curr Osteoporos Rep       Date:  2018-08       Impact factor: 5.096

10.  Development of the Home Fall Hazard Checklist.

Authors:  Christina Ziebart; Neha Dewan; Joshua Tuazon; Joy MacDermid
Journal:  Rehabil Res Pract       Date:  2021-05-31
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.