Literature DB >> 23034970

Symptom interval in pediatric patients with solid tumors: adolescents are at greater risk of late diagnosis.

Laura Veneroni1, Luigi Mariani, Salvatore Lo Vullo, Francesca Favini, Serena Catania, Marco Vajna de Pava, Maura Massimino, Andrea Ferrari.   

Abstract

BACKGROUND: The awareness that adolescents can have cancer is probably insufficient, not only among teenagers and their families, but also among physicians, and adolescent patients are reportedly often referred to qualified cancer institutes after a considerable delay. PROCEDURE: A prospective series of 425 patients (28% of them adolescents) with solid tumors was analyzed to investigate the correlation between symptom interval and age, and the different contributions to symptom interval in terms of the time from symptom onset to the first contact with a doctor (patient delay), referral to the oncologist (referral delay), and final diagnosis (oncologist delay).
RESULTS: The median symptom interval was 47 days for 0 to 14-year-old patients and 137 for those ≥15 years (P < 0.001). The greatest delay in the adolescent group related to the patient delay (63.3% of the total symptom interval).
CONCLUSION: Adolescents are often diagnosed with longer delay as compared to children. The main contribution to symptom interval in adolescents appears to be due to the time they first go to a doctor; however, also the time taken by the physician to the patient to a specialist (oncologist or surgeon) able to define the diagnosis of cancer was longer for adolescents than for younger patients.
Copyright © 2012 Wiley Periodicals, Inc.

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Year:  2012        PMID: 23034970     DOI: 10.1002/pbc.24312

Source DB:  PubMed          Journal:  Pediatr Blood Cancer        ISSN: 1545-5009            Impact factor:   3.167


  9 in total

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3.  Model of Care for Adolescents and Young Adults with Cancer: The Youth Project in Milan.

Authors:  Chiara Magni; Laura Veneroni; Matteo Silva; Michela Casanova; Stefano Chiaravalli; Maura Massimino; Carlo Alfredo Clerici; Andrea Ferrari
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4.  Association of Self-reported Presenting Symptoms With Timeliness of Help-Seeking Among Adolescents and Young Adults With Cancer in the BRIGHTLIGHT Study.

Authors:  Minjoung M Koo; Georgios Lyratzopoulos; Annie Herbert; Gary A Abel; Rachel M Taylor; Julie A Barber; Faith Gibson; Jeremy Whelan; Lorna A Fern
Journal:  JAMA Netw Open       Date:  2020-09-01

5.  Clinical presentation of young people (10-24 years old) with brain tumors: results from the international MOBI-Kids study.

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6.  Symptom Interval and Patient Delay Affect Survival Outcomes in Adolescent Cancer Patients.

Authors:  Song Lee Jin; Seung Min Hahn; Hyo Sun Kim; Yoon Jung Shin; Sun Hee Kim; Yoon Sun Lee; Chuhl Joo Lyu; Jung Woo Han
Journal:  Yonsei Med J       Date:  2016-05       Impact factor: 2.759

7.  Primary Care Use before Cancer Diagnosis in Adolescents and Young Adults - A Nationwide Register Study.

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Journal:  PLoS One       Date:  2016-05-20       Impact factor: 3.240

8.  Determinants of survival of common childhood cancers in Iran.

Authors:  Aliasghar Keramatinia; Maryam Mohseny; Mohammad Esmaeil Akbari; Alireza Mosavi-Jarrahi; Esmat Davoudi Monfared; Farzaneh Amanpour; Ayad Bahadori Monfared; Parastoo Amiri; Maryam Khayamzadeh; Tahereh Alsadat Khoshbin Khoshnazar; Hojjat-Allah Abbaszadeh; Azim Mehrvar; Zeinab Mazloumi; Abolfazl Movafagh
Journal:  J Res Med Sci       Date:  2018-11-28       Impact factor: 1.852

9.  A collateral effect of the COVID-19 pandemic: Delayed diagnosis in pediatric solid tumors.

Authors:  Stefano Chiaravalli; Andrea Ferrari; Giovanna Sironi; Giovanna Gattuso; Luca Bergamaschi; Nadia Puma; Elisabetta Schiavello; Veronica Biassoni; Marta Podda; Cristina Meazza; Filippo Spreafico; Michela Casanova; Monica Terenziani; Roberto Luksch; Maura Massimino
Journal:  Pediatr Blood Cancer       Date:  2020-08-06       Impact factor: 3.838

  9 in total

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