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Literature DB >> 23032577

A highly sensitive fluorescent probe based on simple pyrazoline for Zn2+ in living neuron cells.

Zhe Zhang¹, Fang-Wu Wang, Sheng-Qing Wang, Fei Ge, Bao-Xiang Zhao, Jun-Ying Miao.

Abstract

We develop a pyrazoline-based fluorescent sensor for biological Zn(2+) detection. The sensor shows good binding selectivity for Zn(2+) over competing metal with 40-fold fluorescence enhancement in response to Zn(2+). The new probe is cell-permeable and can be used to detect intracellular zinc ions in living neuron cells.

Entities: Chemical

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Year: 2012 PMID： 23032577 DOI： 10.1039/c2ob26375k

Source DB: PubMed Journal: Org Biomol Chem ISSN： 1477-0520 Impact factor: 3.876

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Cited

7 in total

1. Novel pyrazoline-based selective fluorescent sensor for Hg2+.

Authors: Sheng-Qing Wang; Shu-Yan Liu; Hao-Yan Wang; Xiao-Xin Zheng; Xun Yuan; Yi-Zhi Liu; Jun-Ying Miao; Bao-Xiang Zhao
Journal: J Fluoresc Date: 2013-12-13 Impact factor: 2.217

2. A new thiophenyl pyrazoline fluorescent probe for Cu2+ in aqueous solution and imaging in live cell.

Authors: Meng-Meng Li; Wen-Bo Zhao; Ting-Ting Zhang; Wei-Liu Fan; Yu Xu; Yu Xiao; Jun-Ying Miao; Bao-Xiang Zhao
Journal: J Fluoresc Date: 2013-07-07 Impact factor: 2.217

3. A new pyrazoline-based fluorescent probe for Cu2+ in live cells.

Authors: Meng-Meng Li; Shu-Ya Huang; Hui Ye; Fei Ge; Jun-Ying Miao; Bao-Xiang Zhao
Journal: J Fluoresc Date: 2013-03-21 Impact factor: 2.217

4. Biologically targeted probes for Zn²⁺: a diversity oriented modular "click-S_NAr-click" approach†Electronic supplementary information (ESI) available: Full experimental details including characterisation of all novel compounds can be found in the ESI. See DOI: 10.1039/c4sc01249f.

Authors: J Pancholi; D J Hodson; K Jobe; G A Rutter; S M Goldup; M Watkinson
Journal: Chem Sci Date: 2014-06-27 Impact factor: 9.825

A highly sensitive fluorescent probe based on simple pyrazoline for Zn2+ in living neuron cells.

1. Novel pyrazoline-based selective fluorescent sensor for Hg2+.

2. A new thiophenyl pyrazoline fluorescent probe for Cu2+ in aqueous solution and imaging in live cell.

3. A new pyrazoline-based fluorescent probe for Cu2+ in live cells.

4. Biologically targeted probes for Zn²⁺: a diversity oriented modular "click-S_NAr-click" approach†Electronic supplementary information (ESI) available: Full experimental details including characterisation of all novel compounds can be found in the ESI. See DOI: 10.1039/c4sc01249f.

Review 5. Recent progress in chemosensors based on pyrazole derivatives.

Review 6. Recent Progress in Fluorescent Probes For Metal Ion Detection.

Review 7. Pyrazoline Hybrids as Promising Anticancer Agents: An Up-to-Date Overview.

A highly sensitive fluorescent probe based on simple pyrazoline for Zn2+ in living neuron cells.

1. Novel pyrazoline-based selective fluorescent sensor for Hg2+.

2. A new thiophenyl pyrazoline fluorescent probe for Cu2+ in aqueous solution and imaging in live cell.

3. A new pyrazoline-based fluorescent probe for Cu2+ in live cells.

4. Biologically targeted probes for Zn2+: a diversity oriented modular "click-SNAr-click" approach†Electronic supplementary information (ESI) available: Full experimental details including characterisation of all novel compounds can be found in the ESI. See DOI: 10.1039/c4sc01249f.

Review 5. Recent progress in chemosensors based on pyrazole derivatives.

Review 6. Recent Progress in Fluorescent Probes For Metal Ion Detection.

Review 7. Pyrazoline Hybrids as Promising Anticancer Agents: An Up-to-Date Overview.

4. Biologically targeted probes for Zn²⁺: a diversity oriented modular "click-S_NAr-click" approach†Electronic supplementary information (ESI) available: Full experimental details including characterisation of all novel compounds can be found in the ESI. See DOI: 10.1039/c4sc01249f.