| Literature DB >> 2303252 |
R N Sifers1, F D Ledley, L Reed-Fourquet, D H Ledbetter, S A Ledbetter, S L Woo.
Abstract
A cDNA encoding the complete open reading frame of murine alpha 1-antitrypsin has been cloned and sequenced. The nucleic acid and predicted amino acid sequences show homology to human alpha 1-antitrypsin and demonstrate the preservation of critical structural determinants for intracellular targeting, carbohydrate attachment, and catalytic function. The alpha 1-antitrypsin gene locus (Aat) has been localized on murine chromosome 12E----F by in situ hybridization.Entities:
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Year: 1990 PMID： 2303252 DOI： 10.1016/0888-7543(90)90453-2
Source DB: PubMed Journal: Genomics ISSN： 0888-7543 Impact factor: 5.736