Literature DB >> 2303160

Thyroid hormone stimulates the production of insulin-like growth factor I (IGF-I) by immature rat Sertoli cells.

S Palmero1, M Prati, A Barreca, F Minuto, G Giordano, E Fugassa.   

Abstract

The effects of thyroid hormone on insulin-like growth factor I (IGF-I) production by Sertoli cells isolated from immature rats have been investigated. In Sertoli cells from hypothyroid rats the production of IGF-I was significantly lower than in controls and was greatly stimulated by the administration of triiodothyronine (T3) in vivo. The in vitro addition of physiological doses of T3 (1 nmol/l) significantly increased the production of IGF-I by cultured Sertoli cells indicating a direct action of the hormone on local IGF-I production. Our results suggest the involvement of IGF-I in the thyroid hormone-dependent maturation of testicular function.

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Year:  1990        PMID： 2303160     DOI： 10.1016/0303-7207(90)90170-d

Source DB:  PubMed          Journal:  Mol Cell Endocrinol        ISSN： 0303-7207            Impact factor:   4.102


  11 in total

1.  Tri-iodothyronine effects on Sertoli cell protein turnover in the prepubertal pig.

Authors:  S Palmero; F Bolla; M Benahmed; A M Morera; E Fugassa
Journal:  Cytotechnology       Date:  1993-01       Impact factor: 2.058

Review 2.  Growth factors and testis.

Authors:  G Giordano; P Del Monte; F Minuto
Journal:  J Endocrinol Invest       Date:  1992-01       Impact factor: 4.256

Review 3.  Hormonal control of Sertoli cell metabolism regulates spermatogenesis.

Authors:  Marco G Alves; Luís Rato; Rui A Carvalho; Paula I Moreira; Sílvia Socorro; Pedro F Oliveira
Journal:  Cell Mol Life Sci       Date:  2012-07-20       Impact factor: 9.261

4.  The effects of triiodothyronine on rat testis: a morphometric and immunohistochemical study.

Authors:  Jale Oner; Hakan Oner; Neriman Colakoğlu; Aysel Kükner; Enver Ozan
Journal:  J Mol Histol       Date:  2006-05-30       Impact factor: 2.611

5.  Ontogeny and regulation of variant thyroid hormone receptor isoforms in developing rat testis.

Authors:  E A Jannini; E Carosa; N Rucci; E Screponi; M D'Armiento
Journal:  J Endocrinol Invest       Date:  1999-12       Impact factor: 4.256

Review 6.  The role of thyroid hormone in testicular development and function.

Authors:  Márcia Santos Wagner; Simone Magagnin Wajner; Ana Luiza Maia
Journal:  J Endocrinol       Date:  2008-08-26       Impact factor: 4.286

7.  Enhancement of seminiferous tubular growth and spermatogenesis in testes of rats recovering from early hypothyroidism: a quantitative study.

Authors:  E Meisami; A Najafi; P S Timiras
Journal:  Cell Tissue Res       Date:  1994-03       Impact factor: 5.249

8.  An essential role for insulin and IGF1 receptors in regulating sertoli cell proliferation, testis size, and FSH action in mice.

Authors:  Jean-Luc Pitetti; Pierre Calvel; Céline Zimmermann; Béatrice Conne; Marilena D Papaioannou; Florence Aubry; Christopher R Cederroth; Françoise Urner; Betty Fumel; Michel Crausaz; Mylène Docquier; Pedro Luis Herrera; François Pralong; Marc Germond; Florian Guillou; Bernard Jégou; Serge Nef
Journal:  Mol Endocrinol       Date:  2013-03-21

9.  The emerging role of insulin-like growth factors in testis development and function.

Authors:  Richard J Griffeth; Vanessa Bianda; Serge Nef
Journal:  Basic Clin Androl       Date:  2014-08-18

10.  Expression of dominant-negative thyroid hormone receptor alpha1 in Leydig and Sertoli cells demonstrates no additional defect compared with expression in Sertoli cells only.

Authors:  Betty Fumel; Pascal Froment; Martin Holzenberger; Gabriel Livera; Philippe Monget; Sophie Fouchécourt
Journal:  PLoS One       Date:  2015-03-20       Impact factor: 3.240
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