Literature DB >> 23030489

The future of glioma treatment: stem cells, nanotechnology and personalized medicine.

Maryam Rahman1, Brian Hoh, Nathan Kohler, Erin M Dunbar, Gregory J A Murad.   

Abstract

The development of novel therapies, imaging techniques and insights into the processes that drive growth of CNS tumors have allowed growing enthusiasm for the treatment of CNS malignancies. Despite this energized effort to investigate and treat brain cancer, clinical outcomes for most patients continue to be dismal. Recognition of diverse tumor subtypes, behaviors and outcomes has led to an interest in personalized medicine for the treatment of brain tumors. This new paradigm requires evaluation of the tumor phenotype at the time of diagnosis so that therapy can be specifically tailored to each individual patient. Investigating novel therapies involving stem cells, nanotechnology and molecular medicine will allow diversity of therapeutic options for patients with brain cancer. These exciting new therapeutic strategies for brain tumors are reviewed in this article.

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Year:  2012        PMID: 23030489     DOI: 10.2217/fon.12.111

Source DB:  PubMed          Journal:  Future Oncol        ISSN: 1479-6694            Impact factor:   3.404


  13 in total

1.  Cerebral radiation injury and changes in the brain tissues of rat models with glioma.

Authors:  Lin Sha; Qian Cao; Li Lv; Guoguang Fan
Journal:  Tumour Biol       Date:  2013-11-07

2.  Ketoprofen-loaded polymeric nanocapsules selectively inhibit cancer cell growth in vitro and in preclinical model of glioblastoma multiforme.

Authors:  Elita F da Silveira; Janaine M Chassot; Fernanda C Teixeira; Juliana H Azambuja; Gabriela Debom; Fátima T Beira; Francisco A B Del Pino; Adriana Lourenço; Ana P Horn; Letícia Cruz; Roselia M Spanevello; Elizandra Braganhol
Journal:  Invest New Drugs       Date:  2013-09-27       Impact factor: 3.850

Review 3.  Challenges and opportunities to penetrate the blood-brain barrier for brain cancer therapy.

Authors:  Dannielle H Upton; Caitlin Ung; Sandra M George; Maria Tsoli; Maria Kavallaris; David S Ziegler
Journal:  Theranostics       Date:  2022-06-06       Impact factor: 11.600

4.  Penetrating the Blood-Brain Barrier: Promise of Novel Nanoplatforms and Delivery Vehicles.

Authors:  Iqbal Unnisa Ali; Xiaoyuan Chen
Journal:  ACS Nano       Date:  2015-09-25       Impact factor: 15.881

Review 5.  Klotho, stem cells, and aging.

Authors:  Ao Bian; Javier A Neyra; Ming Zhan; Ming Chang Hu
Journal:  Clin Interv Aging       Date:  2015-08-04       Impact factor: 4.458

Review 6.  Molecular culprits generating brain tumor stem cells.

Authors:  Se-Yeong Oh; Hyunggee Kim
Journal:  Brain Tumor Res Treat       Date:  2013-04-30

7.  Bionanotechnology and the future of glioma.

Authors:  Peter A Chiarelli; Forrest M Kievit; Miqin Zhang; Richard G Ellenbogen
Journal:  Surg Neurol Int       Date:  2015-02-13

8.  Anti-cancer Therapies in High Grade Gliomas.

Authors:  Cristiana Pistol Tanase; Ana-Maria Enciu; Simona Mihai; Ana Iulia Neagu; Bogdan Calenic; Maria Linda Cruceru
Journal:  Curr Proteomics       Date:  2013-09       Impact factor: 0.837

9.  The prognostic value of Foxp3+ tumor-infiltrating lymphocytes in patients with glioblastoma.

Authors:  Qi Yue; Xin Zhang; Hong-Xing Ye; Yin Wang; Zun-Guo Du; Yu Yao; Ying Mao
Journal:  J Neurooncol       Date:  2013-11-26       Impact factor: 4.130

10.  Conditioned media from human adipose tissue-derived mesenchymal stem cells and umbilical cord-derived mesenchymal stem cells efficiently induced the apoptosis and differentiation in human glioma cell lines in vitro.

Authors:  Chao Yang; Deqiang Lei; Weixiang Ouyang; Jinghua Ren; Huiyu Li; Jingqiong Hu; Shiang Huang
Journal:  Biomed Res Int       Date:  2014-05-27       Impact factor: 3.411

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