Literature DB >> 230303

Anticellular effects of 9-(2-hydroxyethoxymethyl) guanine against herpes simplex virus-transformed cells.

Y Nishiyama, F Rapp.   

Abstract

The guanine derivative 9-(2-hydroxyethoxymethyl) guanine (acycloguanosine), a potent inhibitor of herpes simplex virus (HSV) multiplication, was found to have marked anticellular activity against HSV-transformed thymidine kinase-positive cells. HSV type I-transformed cells were more sensitive to the drug than HSV type 2-transformed cells.

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Year:  1979        PMID： 230303     DOI： 10.1099/0022-1317-45-1-227

Source DB:  PubMed          Journal:  J Gen Virol        ISSN： 0022-1317            Impact factor:   3.891


  11 in total

1.  Properties of cells carrying the herpes simplex virus type 2 thymidine kinase gene: mechanisms of reversion to a thymidine kinase-negative phenotype.

Authors:  K F Bastow; G Darby; P Wildy; A C Minson
Journal:  J Virol       Date:  1980-12       Impact factor: 5.103

2.  Inhibition by ganciclovir of cell growth and DNA synthesis of cells biochemically transformed with herpesvirus genetic information.

Authors:  M H St Clair; C U Lambe; P A Furman
Journal:  Antimicrob Agents Chemother       Date:  1987-06       Impact factor: 5.191

Review 3.  Please stand by: how oncolytic viruses impact bystander cells.

Authors:  Leslee Sprague; Lynne Braidwood; Joe Conner; Kevin A Cassady; Fabian Benencia; Timothy P Cripe
Journal:  Future Virol       Date:  2018-08-08       Impact factor: 1.831

4.  Adenovirus-mediated interleukin-12 gene therapy for metastatic colon carcinoma.

Authors:  M Caruso; K Pham-Nguyen; Y L Kwong; B Xu; K I Kosai; M Finegold; S L Woo; S H Chen
Journal:  Proc Natl Acad Sci U S A       Date:  1996-10-15       Impact factor: 11.205

5.  Intercellular trafficking and cytotoxicity of recombinant HSV-1 thymidine kinase fused with HSV-2 US11 RXP repeat peptide.

Authors:  Chenhong Luo; Akihiro Nawa; Youhei Yamauchi; Shinichi Kohno; Youko Ushijima; Fumi Goshima; Fumitaka Kikkawa; Yukihiro Nishiyama
Journal:  Virus Genes       Date:  2006-08-22       Impact factor: 2.332

6.  Inhibition of cellular alpha and virally induced deoxyribonucleic acid polymerases by the triphosphate of acyclovir.

Authors:  M H St Clair; P A Furman; C M Lubbers; G B Elion
Journal:  Antimicrob Agents Chemother       Date:  1980-11       Impact factor: 5.191

7.  Regression of established macroscopic liver metastases after in situ transduction of a suicide gene.

Authors:  M Caruso; Y Panis; S Gagandeep; D Houssin; J L Salzmann; D Klatzmann
Journal:  Proc Natl Acad Sci U S A       Date:  1993-08-01       Impact factor: 11.205

8.  Fertile homozygous transgenic mice expressing a functional truncated herpes simplex thymidine kinase delta TK gene.

Authors:  J L Cohen; O Boyer; B Salomon; R Onclerco; D Depetris; L Lejeune; V Dubus-Bonnet; S Bruel; F Charlotte; M G Mattéï; D Klatzmann
Journal:  Transgenic Res       Date:  1998-09       Impact factor: 2.788

9.  Effect of acyclovir and interferon on human hematopoietic progenitor cells.

Authors:  L M Parker; J M Lipton; N Binder; E L Crawford; M Kudisch; M J Levin
Journal:  Antimicrob Agents Chemother       Date:  1982-01       Impact factor: 5.191

Review 10.  Retroviral transfer of HSV1-TK gene into human lung cancer cell line.

Authors:  Y Hasegawa; N Emi; K Shimokata
Journal:  J Mol Med (Berl)       Date:  1995-03       Impact factor: 4.599
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