Literature DB >> 2302662

Orchidectomy alone for stage I seminoma of the testis.

G M Duchesne1, A Horwich, D P Dearnaley, J Nicholls, G Jay, M J Peckham, W F Hendry.   

Abstract

Between 1983 and 1988, 113 patients with Stage I seminoma were managed after orchidectomy by surveillance rather than adjuvant radiotherapy. The actuarial risk of relapse at 3 years was 15.8% (95% confidence interval, 7.8% to 23.8%). All 13 patients who experienced a relapse are currently in remission (4 to 45 months after salvage therapy), although 5 suffered second relapses requiring further treatment. Close surveillance is a safe alternative to adjuvant radiotherapy in Stage I seminoma. However, the policy requires prolonged observation of patients with intensive use of resources. Therefore, adjuvant radiotherapy should be considered the treatment of choice.

Entities:  

Mesh:

Year:  1990        PMID: 2302662     DOI: 10.1002/1097-0142(19900301)65:5<1115::aid-cncr2820650513>3.0.co;2-6

Source DB:  PubMed          Journal:  Cancer        ISSN: 0008-543X            Impact factor:   6.860


  9 in total

1.  [Testicular cancer--is there an indication for adjuvant or neoadjuvant systemic therapy?].

Authors:  S Langenkamp; P Albers
Journal:  Urologe A       Date:  2007-10       Impact factor: 0.639

2.  Treatment of stage I seminoma: should beta-HCG positive seminoma be treated aggressively?

Authors:  K Suzuki; H Nakazato; K Kurokawa; T Suzuki; K Suzuki; H Yamanaka
Journal:  Int Urol Nephrol       Date:  1998       Impact factor: 2.370

Review 3.  Contemporary management of early stage testicular seminoma.

Authors:  Ahmet Murat Aydin; Logan Zemp; Salim K Cheriyan; Wade J Sexton; Peter A S Johnstone
Journal:  Transl Androl Urol       Date:  2020-01

Review 4.  Clinical stage I seminoma: the case for surveillance.

Authors:  Nathan Lawrentschuk; Neil Fleshner
Journal:  World J Urol       Date:  2009-06-11       Impact factor: 4.226

5.  Influence of year of diagnosis, patient age, and sociodemographic status on recommending adjuvant radiation treatment for stage I testicular seminoma.

Authors:  Karen E Hoffman; Ming-Hui Chen; Rinaa S Punglia; Clair J Beard; Anthony V D'Amico
Journal:  J Clin Oncol       Date:  2008-08-20       Impact factor: 44.544

Review 6.  Treatment of stage I testicular germ-cell tumors.

Authors:  Jorge Aparicio; J R Germà
Journal:  Med Oncol       Date:  2006       Impact factor: 3.738

7.  An assessment of combined tumour markers in patients with seminoma: placental alkaline phosphatase (PLAP), lactate dehydrogenase (LD) and beta human chorionic gonadotrophin (beta HCG).

Authors:  A J Munro; O S Nielsen; W Duncan; J Sturgeon; M K Gospodarowicz; A Malkin; G M Thomas; M A Jewett
Journal:  Br J Cancer       Date:  1991-09       Impact factor: 7.640

8.  Surveillance following orchidectomy for stage I testicular seminoma.

Authors:  A Horwich; N Alsanjari; R A'Hern; J Nicholls; D P Dearnaley; C Fisher
Journal:  Br J Cancer       Date:  1992-05       Impact factor: 7.640

9.  An analysis of surveillance for stage I combined teratoma--seminoma of the testis.

Authors:  R Thomas; D Dearnaley; J Nicholls; A Norman; S Sampson; A Horwich
Journal:  Br J Cancer       Date:  1996-07       Impact factor: 7.640

  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.