Literature DB >> 2302568

Gangliosides improve synaptic transmission in dentate gyrus of hippocampal rat slices.

O A Ramirez1, R A Gomez, H F Carrer.   

Abstract

The effect of perfusion with gangliosides (1 x 10(-6) M) on the response evoked in the granule cell layer of dentate gyrus by stimulation of perforant path in hippocampal rat slices was studied. Gangliosides induced both a decrease in the frequency threshold of stimulation necessary to generate long-term potentiation (LTP) and greater potentiation than under control conditions. It is proposed that gangliosides improve the mechanisms responsible for synaptic plasticity which generate LTP.

Entities:  

Mesh：

Substances：

Year:  1990        PMID： 2302568     DOI： 10.1016/0006-8993(90)91264-h

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  11 in total

Review 1.  Pathophysiological actions of neuropathy-related anti-ganglioside antibodies at the neuromuscular junction.

Authors:  Jaap J Plomp; Hugh J Willison
Journal:  J Physiol       Date:  2009-06-29       Impact factor: 5.182

2.  Uptake of exogenous gangliosides by rat brain synaptosomes.

Authors:  H P Young; Z F Christian; R Cabeza; L N Irwin
Journal:  Neurochem Res       Date:  1998-12       Impact factor: 3.996

3.  The influence of exogenous gangliosides on the dynamics of the development of prolonged posttetanic potentiation.

Authors:  N V Egorushkina; A S Ratushnyak; I V Egorushkin
Journal:  Neurosci Behav Physiol       Date:  1993 Sep-Oct

4.  Complex gangliosides at the neuromuscular junction are membrane receptors for autoantibodies and botulinum neurotoxin but redundant for normal synaptic function.

Authors:  Roland W M Bullens; Graham M O'Hanlon; Eric Wagner; Peter C Molenaar; Keiko Furukawa; Koichi Furukawa; Jaap J Plomp; Hugh J Willison
Journal:  J Neurosci       Date:  2002-08-15       Impact factor: 6.167

5.  Mice with disrupted GM2/GD2 synthase gene lack complex gangliosides but exhibit only subtle defects in their nervous system.

Authors:  K Takamiya; A Yamamoto; K Furukawa; S Yamashiro; M Shin; M Okada; S Fukumoto; M Haraguchi; N Takeda; K Fujimura; M Sakae; M Kishikawa; H Shiku; K Furukawa; S Aizawa
Journal:  Proc Natl Acad Sci U S A       Date:  1996-10-01       Impact factor: 11.205

6.  Analysis of the effects of antibodies to gangliosides on the electrical activity of Retzius neurons in the leech and on the functional activity of influx sodium current channels.

Authors:  S S Sergeeva; E Zapryanova; O S Sotnikov; D Deleva; A Fil'chev
Journal:  Neurosci Behav Physiol       Date:  2004-07

Review 7.  The pre-synaptic motor nerve terminal as a site for antibody-mediated neurotoxicity in autoimmune neuropathies and synaptopathies.

Authors:  Simon N Fewou; Jaap J Plomp; Hugh J Willison
Journal:  J Anat       Date:  2013-08-13       Impact factor: 2.610

8.  MALDI imaging delineates hippocampal glycosphingolipid changes associated with neurotoxin induced proteopathy following neonatal BMAA exposure.

Authors:  Oskar Karlsson; Wojciech Michno; Yusuf Ransome; Jörg Hanrieder
Journal:  Biochim Biophys Acta Proteins Proteom       Date:  2016-12-09       Impact factor: 3.036

Review 9.  Ganglioside/protein kinase signals triggering cytoskeletal actin reorganization.

Authors:  Hideyoshi Higashi; Nai Hong Chen
Journal:  Glycoconj J       Date:  2004       Impact factor: 3.009

10.  Imaging mass spectrometry technology and application on ganglioside study; visualization of age-dependent accumulation of C20-ganglioside molecular species in the mouse hippocampus.

Authors:  Yuki Sugiura; Shuichi Shimma; Yoshiyuki Konishi; Maki K Yamada; Mitsutoshi Setou
Journal:  PLoS One       Date:  2008-09-18       Impact factor: 3.240
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.