Literature DB >> 23025586

Management of severe idiopathic oligohydramnios: is antepartum transabdominal amnioinfusion really a treatment option?

Zoltan Kozinszky1, Norbert Pásztor, Melinda Vanya, János Sikovanyecz, Attila Pál.   

Abstract

OBJECTIVE: The aim of this study was an evaluation of the role of antepartum transabdominal amnioinfusion (APTA) in the management of severe idiopathic oligohydramnios with a view to improving the pregnancy outcome.
METHODS: The study comprised an analysis of 20 pregnant women with severe oligohydramnios who were treated with APTA in 2009 and 2012. The pregnancy outcomes and the complications of the procedure were analysed.
RESULTS: The mean gestational age at first treatment was 22 weeks 3 days. The preprocedure amniotic fluid index of <5 cm was restored by the treatment to 8 cm. More than a half of the pregnancies (66.7%, 8/12) treated with APTA finished with spontaneous abortion in the second trimester, mostly due to rupture of the membranes (as a consequence of retroamniotic filling with saline in four cases). The later the oligohydramnios developed, the higher the probability of a significant prolongation of the gestation.
CONCLUSIONS: Although APTA is a useful procedure in the management of severe oligohydramnios, it may be followed by a relatively high rate of rupture of the membranes, particularly in the second trimester. Paradoxically, a higher volume of infused saline into the amniotic cavity is associated with a significantly lower risk of rupture.

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Year:  2012        PMID: 23025586     DOI: 10.3109/14767058.2012.733753

Source DB:  PubMed          Journal:  J Matern Fetal Neonatal Med        ISSN: 1476-4954


  3 in total

Review 1.  Lower urinary tract obstruction: fetal intervention based on prenatal staging.

Authors:  Rodrigo Ruano; Timothy Dunn; Michael C Braun; Joseph R Angelo; Adnan Safdar
Journal:  Pediatr Nephrol       Date:  2017-07-21       Impact factor: 3.714

Review 2.  Severe antenatally diagnosed renal disorders: background, prognosis and practical approach.

Authors:  Wiebke Aulbert; Markus J Kemper
Journal:  Pediatr Nephrol       Date:  2015-06-17       Impact factor: 3.714

3.  Changes in the Intra-Amniotic Pressure following Transabdominal Amnioinfusion during Pregnancy.

Authors:  Daisuke Katsura; Yuichiro Takahashi; Shigenori Iwagaki; Rika Chiaki; Kazuhiko Asai; Masako Koike; Takashi Murakami
Journal:  Biomed Hub       Date:  2021-10-05
  3 in total

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