Literature DB >> 23024739

Severe erosive esophagitis developing after gastric ulcer formation.

Takatsugu Yamamoto1, Koichiro Abe, Hajime Anjiki, Taro Ishii, Yasushi Kuyama.   

Abstract

A 90-year-old woman visited to our institute due to postprandial obstructive sensation of the esophagus. She had suffered from ischemic heart disease and diabetes mellitus, and taken low-dose aspirin for prophylaxis. She also had a history of a large ulcer located on the upper gastric body at 81 years-old. Esophago-gastric junction was normal excepting mild hiatal hernia at that time. The esophagogastroduodenoscopy showed a lump of food at the lower esophagus with severe stricture and mucosal injury. Rabeprazole 20 mg per day was given, and both the inflammatory change and the symptoms improved after the prescription. A probable reason of the development is impaired gastroesophageal motility and acid regurgitation induced by gastric deformity caused after ulcer formation.

Entities:  

Keywords:  Elderly; Esophagitis; Peptic ulcer

Year:  2012        PMID: 23024739      PMCID: PMC3449434          DOI: 10.4021/jocmr895w

Source DB:  PubMed          Journal:  J Clin Med Res        ISSN: 1918-3003


Introduction

The prevalence of reflux esophagitis increases in association with westernized diet and advanced aging society in Japan. However, it remains uncertain how esophagitis develops [1]. Here we report on a case of esophagitis appearing after 9 years.

Case Report

A 90-year-old woman visited to our institute due to postprandial obstructive sensation of the esophagus. She had suffered from ischemic heart disease and diabetes mellitus for over 30 years, and taken low-dose aspirin for prophylaxis. She also had a history of a large peptic ulcer located on the upper gastric body at 81-years old, and taken lansoprazole 15 mg per day since then (Fig. 1). Esophago-gastric junction was normal excepting mild hiatal hernia at that time (Fig. 2). The esophagogastroduodenoscopy showed a lump of food at the lower esophagus with severe stricture and mucosal injury (Fig. 3, 4). Gastric ulcer scar was also found without recurrence. Rabeprazole 20 mg per day was given, and both the inflammatory change and the symptoms improved after the prescription.
Figure 1

The patient had a large gastric ulcer when she was 81 years old.

Figure 2

Slight hiatal hernia was seen at that time.

Figure 3

Esophagogastroduodenoscopy performed at age 90 showed a lump of food at the lower esophagus.

Figure 4

Esophageal stricture with severe mucosal injury was found after removal of food.

The patient had a large gastric ulcer when she was 81 years old. Slight hiatal hernia was seen at that time. Esophagogastroduodenoscopy performed at age 90 showed a lump of food at the lower esophagus. Esophageal stricture with severe mucosal injury was found after removal of food.

Discussion

We described on the case with severe esophagitis developed 9 years after gastric ulcer formation. A probable reason of the disease is impaired gastroesophageal motility and acid regurgitation induced by gastric deformity. Because the course of developing esophagitis remains unknown, the present case gives us images that show how severe esophagitis develop.
  1 in total

1.  Disease progression in gastro-oesophageal reflux disease as determined by repeat oesophageal pH monitoring and endoscopy 3 to 4.5 years after diagnosis.

Authors:  N I McDougall; B T Johnston; J S Collins; R J McFarland; A H Love
Journal:  Eur J Gastroenterol Hepatol       Date:  1997-12       Impact factor: 2.566

  1 in total

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