Literature DB >> 23024715

Rituals can kill - A fatal case of brucine poisoning.

Basavaprabhu Achappa1, Deepak Madi, Y P Raghavendra Babu, Soundarya Mahalingam.   

Abstract

In some parts of India people follow a religious ritual of drinking an herbal preparation made from the bark of the Alstonia scholaris tree (Blackboard tree) on the day of the new moon in the month of July. This tree could be easily confused with the Strychnos nux vomica tree. Brucine is the predominant alkaloid present in the bark of the Strychnos nux vomica tree. The toxicological property of brucine is similar to strychnine. Brucine is a neurotoxin. A 29-year-old male presented with a history of consumption of an herbal preparation made from the bark of the Strychnos nux vomica tree confusing it for Alstonia scholaris. Soon after, he developed convulsions and later died in hospital on the same day. The aim of this case report is to highlight the fact that people must be cautious when they follow religious rituals.

Entities:  

Keywords:  Alstonia scholaris; Brucine; poisoning; strychnine

Year:  2012        PMID: 23024715      PMCID: PMC3442185          DOI: 10.4066/AMJ.2012.1293

Source DB:  PubMed          Journal:  Australas Med J        ISSN: 1836-1935


  5 in total

1.  Brucine lethality in mice.

Authors:  M H Malone; K M St John-Allan; E Bejar
Journal:  J Ethnopharmacol       Date:  1992-01       Impact factor: 4.360

2.  Fatal intoxication due to brucine.

Authors:  Jörg Teske; Jens-Peter Weller; Urs-Vito Albrecht; Armin Fieguth
Journal:  J Anal Toxicol       Date:  2011-05       Impact factor: 3.367

3.  Strychnine poisoning as an unusual cause of convulsions.

Authors:  D J Burn; C R Tomson; J Seviour; G Dale
Journal:  Postgrad Med J       Date:  1989-08       Impact factor: 2.401

4.  A rare case of brucine poisoning complicated by rhabdomyolysis and acute renal failure.

Authors:  B Sadananda Naik; M Chakrapani
Journal:  Malays J Pathol       Date:  2009-06       Impact factor: 0.656

5.  Strychnine poisoning: a case report.

Authors:  R Sarvesvaran
Journal:  Malays J Pathol       Date:  1992-06       Impact factor: 0.656

  5 in total

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