Rizwana Solanki1, Nandita Maitra. 1. Department of Obstetrics and Gynecology, Government Medical College, Baroda, India.
Abstract
OBJECTIVE: To assess maternal cardiovascular function using echocardiography in normal and preeclamptic women in the third trimester of pregnancy. METHODS: 40 subjects, 20 with preeclampsia and 20 normotensive controls with >34 weeks gestation and singleton pregnancy were recruited. Baseline characteristics, maternal and fetal outcome were studied with systolic and diastolic parameters on echocardiography. RESULTS: The following parameters were higher in preeclamptic subjects as compared to normotensive controls-mean cardiac output (66.85 ± 4.56 ml/min vs. 56.1 ± 1.77 ml/min); mean LV diastolic mass (131.15 ± 16.85 vs. 104.90 ± 23.17 g); systolic mass (88.5 ± 7.34 vs. 83.33 ± 23.84 g); total vascular resistance (1396.85 ± 150.2 vs. 1204.5 ± 71.182 dyne, s cm(5)). Women with preeclampsia delivered smaller babies (2410 ± 426.16 g) as compared to normotensive controls (2895 ± 276.20 g). Student 't' test was used as a test of significance. CONCLUSION: Women with preeclampsia have significant systolic and diastolic dysfunction compared to normotensive controls. Blood pressure monitoring alone is insufficient to identify effectively, risk of cardiovascular complications in these subjects.
OBJECTIVE: To assess maternal cardiovascular function using echocardiography in normal and preeclamptic women in the third trimester of pregnancy. METHODS: 40 subjects, 20 with preeclampsia and 20 normotensive controls with >34 weeks gestation and singleton pregnancy were recruited. Baseline characteristics, maternal and fetal outcome were studied with systolic and diastolic parameters on echocardiography. RESULTS: The following parameters were higher in preeclamptic subjects as compared to normotensive controls-mean cardiac output (66.85 ± 4.56 ml/min vs. 56.1 ± 1.77 ml/min); mean LV diastolic mass (131.15 ± 16.85 vs. 104.90 ± 23.17 g); systolic mass (88.5 ± 7.34 vs. 83.33 ± 23.84 g); total vascular resistance (1396.85 ± 150.2 vs. 1204.5 ± 71.182 dyne, s cm(5)). Women with preeclampsia delivered smaller babies (2410 ± 426.16 g) as compared to normotensive controls (2895 ± 276.20 g). Student 't' test was used as a test of significance. CONCLUSION:Women with preeclampsia have significant systolic and diastolic dysfunction compared to normotensive controls. Blood pressure monitoring alone is insufficient to identify effectively, risk of cardiovascular complications in these subjects.
Authors: H Valensise; G P Novelli; B Vasapollo; G Di Ruzza; M E Romanini; M Marchei; G Larciprete; D Manfellotto; C Romanini; A Galante Journal: Hypertension Date: 2001-05 Impact factor: 10.190
Authors: A Poppas; S G Shroff; C E Korcarz; J U Hibbard; D S Berger; M D Lindheimer; R M Lang Journal: Circulation Date: 1997-05-20 Impact factor: 29.690