Literature DB >> 23024483

Primary biliary cirrhosis presenting with gastritis, hyperlipidemia and marked weight loss.

Moushumi Lodh1, Debkanta Pradhan, Abhishek Mukherjee.   

Abstract

We report an unusual presentation of primary biliary cirrhosis. We present the case of a 31-year-old Indian woman who presented to the hospital with non specific complaints of gastritis, reduced appetite and marked weight loss and no complaints of pruritus. Serum liver enzymes were elevated. Cytoplasmic pattern of antinuclear antibodies was found on immunofluorescence microscopy accompanied by positive anti smooth muscle antibody. Endoscopy revealed esophageal varices. Following a liver biopsy, the diagnosis of primary biliary cirrhosis was made. It is important to consider the diagnosis of hepatic cirrhosis when patient presents with gastritis, reduced appetite and marked weight loss in both the presence and absence of ascites.

Entities:  

Keywords:  AMA; ANA; ASMA; PBC; Primary biliary cirrhosis; Pruritus

Year:  2011        PMID: 23024483      PMCID: PMC3210241          DOI: 10.1007/s12291-011-0148-9

Source DB:  PubMed          Journal:  Indian J Clin Biochem        ISSN: 0970-1915


  8 in total

1.  Two cases of inflammatory bowel disease diagnosed in the course of primary biliary cirrhosis.

Authors:  Osamu Arai; Hiroshi Ikeda; Hirokazu Mouri; Kenji Notohara; Kazuhiro Matsueda
Journal:  Nihon Shokakibyo Gakkai Zasshi       Date:  2010-06

Review 2.  Primary biliary cirrhosis.

Authors:  Marshall M Kaplan; M Eric Gershwin
Journal:  N Engl J Med       Date:  2005-09-22       Impact factor: 91.245

3.  38-year-old woman with abnormal liver enzymes and hyperlipidemia.

Authors:  Marina G Silveira; Keith D Lindor
Journal:  Mayo Clin Proc       Date:  2009-06       Impact factor: 7.616

4.  Primary biliary cirrhosis.

Authors:  Carlo Selmi; Christopher L Bowlus; M Eric Gershwin; Ross L Coppel
Journal:  Lancet       Date:  2011-04-28       Impact factor: 79.321

5.  Variants at IRF5-TNPO3, 17q12-21 and MMEL1 are associated with primary biliary cirrhosis.

Authors:  Gideon M Hirschfield; Xiangdong Liu; Younghun Han; Ivan P Gorlov; Yan Lu; Chun Xu; Yue Lu; Wei Chen; Brian D Juran; Catalina Coltescu; Andrew L Mason; Piotr Milkiewicz; Robert P Myers; Joseph A Odin; Velimir A Luketic; Danute Speiciene; Catherine Vincent; Cynthia Levy; Peter K Gregersen; Jinyi Zhang; E Jenny Heathcote; Konstantinos N Lazaridis; Christopher I Amos; Katherine A Siminovitch
Journal:  Nat Genet       Date:  2010-07-18       Impact factor: 38.330

6.  Primary biliary cirrhosis in India.

Authors:  Shiv Kumar Sarin; Rajnish Monga; Bimaljeet Singh Sandhu; Barjesh Chander Sharma; Puja Sakhuja; Veena Malhotra
Journal:  Hepatobiliary Pancreat Dis Int       Date:  2006-02

7.  A lipoprotein characterizing obstructive jaundice. I. Method for quantitative separation and identification of lipoproteins in jaundiced subjects.

Authors:  D Seidel; P Alaupovic; R H Furman
Journal:  J Clin Invest       Date:  1969-07       Impact factor: 14.808

8.  The role of CXCR3 in the induction of primary biliary cirrhosis.

Authors:  Wen Zhang; Yunyun Fei; Jinming Gao; Bin Liu; Fengchun Zhang
Journal:  Clin Dev Immunol       Date:  2011-05-02
  8 in total

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