OBJECTIVE: To determine whether group B Streptococcus (GBS)-colonized pregnant women have an increased prevalence of GBS colonization in subsequent pregnancies. STUDY DESIGN: This retrospective cohort study compared the prevalence of GBS colonization in initial and subsequent pregnancies of 158 women with two or more deliveries at a Midwest institution since the initiation of universal screening for GBS. RESULTS: The GBS colonization rate in index pregnancies was 20%. Colonization rate in subsequent pregnancies for initially GBS-colonized women was 42% compared with 19% for women who were not colonized with GBS in the index pregnancy (p = 0.009). The relative risk for GBS-colonized women to be GBS-colonized in subsequent pregnancies was 2.2 (confidence interval = 1.3 to 3.8). CONCLUSION: Previous GBS colonization is a risk factor for GBS colonization in subsequent pregnancies. Consideration of intrapartum chemoprophylaxis in women with a history of GBS colonization, assuming current colonization status is unknown, warrants further investigation. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
OBJECTIVE: To determine whether group B Streptococcus (GBS)-colonized pregnant women have an increased prevalence of GBS colonization in subsequent pregnancies. STUDY DESIGN: This retrospective cohort study compared the prevalence of GBS colonization in initial and subsequent pregnancies of 158 women with two or more deliveries at a Midwest institution since the initiation of universal screening for GBS. RESULTS: The GBS colonization rate in index pregnancies was 20%. Colonization rate in subsequent pregnancies for initially GBS-colonized women was 42% compared with 19% for women who were not colonized with GBS in the index pregnancy (p = 0.009). The relative risk for GBS-colonized women to be GBS-colonized in subsequent pregnancies was 2.2 (confidence interval = 1.3 to 3.8). CONCLUSION: Previous GBS colonization is a risk factor for GBS colonization in subsequent pregnancies. Consideration of intrapartum chemoprophylaxis in women with a history of GBS colonization, assuming current colonization status is unknown, warrants further investigation. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
Authors: Mark K Santillan; Kimberly K Leslie; Wendy S Hamilton; Brenda J Boese; Monika Ahuja; Stephen K Hunter; Donna A Santillan Journal: Eur J Obstet Gynecol Reprod Biol Date: 2014-06-02 Impact factor: 2.435
Authors: Gerald A Capraro; Sajel Lala; Khaldia Khaled; Elizabeth Gosciniak; Brianna Saadat; Sarah M Alvarez; Seema Kumar; Tara Calhoun; Edward Landry; Gloria Caldito; Joseph A Bocchini; John A Vanchiere Journal: Antimicrob Resist Infect Control Date: 2020-11-04 Impact factor: 4.887