Literature DB >> 23023525

Closed globe macular injuries after blasts in combat.

Brandon N Phillips1, Dal W Chun, Marcus Colyer.   

Abstract

PURPOSE: To describe the macular findings after closed globe ocular injuries sustained from blasts.
METHODS: A retrospective chart review from February 2003 to March 2010 of all soldiers with closed globe ocular injuries sustained during combat with macular findings of trauma on examination was completed.
RESULTS: There were 36 eyes that met the inclusion criteria. The mean age of the soldiers was 29.5 years and 97% were men. The average follow-up time was 18.6 months. Improvised explosive device blasts accounted for 86% of injuries. Forty-five percent of soldiers had bilateral ocular injuries. Eight of 36 eyes (22.2%) developed a macular hole. One eye had spontaneous closure and five eyes underwent surgical repair. There was a range of macular findings from retinal pigment epitheliopathy alone to retinal pigment epitheliopathy with full-thickness atrophy. Eight eyes (22.2%) had macular scarring on examination but no optical coherence tomography study. One eye (2.8%) developed phthisis bulbi. Fifteen eyes (42%) had an orbital fracture. Seven eyes (19%) sustained optic neuropathy.
CONCLUSION: Closed globe injuries after blasts resulted in a spectrum of macular findings. The integrity of the foveal inner segment/outer segment junction was the most important retinal factor in visual outcomes. Orbital fractures were not found to be a risk factor for developing optic neuropathy and may improve visual outcomes. The rate of long-term complications is unknown, and it is important for ophthalmologists to follow these patients closely.

Entities:  

Mesh:

Year:  2013        PMID: 23023525     DOI: 10.1097/IAE.0b013e318261a726

Source DB:  PubMed          Journal:  Retina        ISSN: 0275-004X            Impact factor:   4.256


  7 in total

1.  Assessment of necroptosis in the retina in a repeated primary ocular blast injury mouse model.

Authors:  Chloe N Thomas; Ella Courtie; Alexandra Bernardo-Colón; Gareth Essex; Tonia S Rex; Zubair Ahmed; Richard J Blanch
Journal:  Exp Eye Res       Date:  2020-06-06       Impact factor: 3.467

2.  Outer retinal structure after closed-globe blunt ocular trauma.

Authors:  John A Flatter; Robert F Cooper; Michael J Dubow; Alexander Pinhas; Ravi S Singh; Rashmi Kapur; Nishit Shah; Ryan D Walsh; Sang H Hong; David V Weinberg; Kimberly E Stepien; William J Wirostko; Scott Robison; Alfredo Dubra; Richard B Rosen; Thomas B Connor; Joseph Carroll
Journal:  Retina       Date:  2014-10       Impact factor: 4.256

3.  Eye-Directed Overpressure Airwave-Induced Trauma Causes Lasting Damage to the Anterior and Posterior Globe: A Model for Testing Cell-Based Therapies.

Authors:  Courtney Bricker-Anthony; Jessica Hines-Beard; Tonia S Rex
Journal:  J Ocul Pharmacol Ther       Date:  2016-03-16       Impact factor: 2.671

4.  Rapid Repeat Exposure to Subthreshold Trauma Causes Synergistic Axonal Damage and Functional Deficits in the Visual Pathway in a Mouse Model.

Authors:  Victoria Vest; Alexandra Bernardo-Colón; Dexter Watkins; Bohan Kim; Tonia S Rex
Journal:  J Neurotrauma       Date:  2019-01-08       Impact factor: 5.269

5.  Molecular changes and vision loss in a mouse model of closed-globe blast trauma.

Authors:  Courtney Bricker-Anthony; Jessica Hines-Beard; Tonia S Rex
Journal:  Invest Ophthalmol Vis Sci       Date:  2014-07-03       Impact factor: 4.799

6.  Exacerbation of blast-induced ocular trauma by an immune response.

Authors:  Courtney Bricker-Anthony; Jessica Hines-Beard; Lauren D'Surney; Tonia S Rex
Journal:  J Neuroinflammation       Date:  2014-11-29       Impact factor: 8.322

7.  Hypothermia Prevents Retinal Damage Generated by Optic Nerve Trauma in the Rat.

Authors:  Manuel Rey-Funes; Ignacio M Larrayoz; Daniela S Contartese; Manuel Soliño; Anibal Sarotto; Martín Bustelo; Martín Bruno; Verónica B Dorfman; César F Loidl; Alfredo Martínez
Journal:  Sci Rep       Date:  2017-07-31       Impact factor: 4.379

  7 in total

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