Literature DB >> 23023026

A case of methanol intoxication caused by methomyl pesticide ingestion.

H W Gil1, J R Hong, H Y Song, S Y Hong.   

Abstract

When clinicians treat patients with pesticide poisoning, they often pay attention only to the chief toxic agent and ignore the toxicity of the pesticide's additives or solvents. Occasionally, however, a solvent (e.g. methanol) may itself be the cause of poisoning. We report a case of acute methanol intoxication that occurred after ingestion of a methomyl pesticide that contained methanol as an additive. A 49-year-old man was brought to the emergency department in an unconscious state after ingestion of 20 ml of a carbamate pesticide (chief ingredient: methomyl; active ingredient: methanol). Upon arrival, he was semicomatose and did not breathe spontaneously; however, his cholinesterase level was within normal limits and cholinergic symptoms were not observed. High anion gap metabolic acidosis was present. His blood ethanol level was 74.8 mg/dL. The urine methanol level was 55.60 mg/dL, and urine ethanol level was 22.0 mg/dL. He was treated with hemodialysis; subsequently, his metabolic acidosis resolved and he returned to normal mental status. We guessed that methanol, as the solvent of the methomyl, had produced the symptoms. When treating pesticide-poisoned patients, clinicians should identify the solvent used in the pesticide, because solvents such as methanol may exacerbate the symptoms of poisoned patients.

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Year:  2012        PMID: 23023026     DOI: 10.1177/0960327112459532

Source DB:  PubMed          Journal:  Hum Exp Toxicol        ISSN: 0960-3271            Impact factor:   2.903


  4 in total

1.  Methanol Intoxication After Suicidal Ingestion of Liquid Rodenticides: A Report of Two Cases.

Authors:  Chan-Wa Cheong; Shao-Feng Liao; Chun-Kuei Chen; Chen-June Seak; Hsien-Yi Chen
Journal:  J Acute Med       Date:  2022-03-01

2.  Psychiatric comorbidities in patients with intentional methanol intoxication.

Authors:  Wei-Sheng Yang; Tzung-Hai Yen; Yeong-Yuh Juang; Shwu-Hua Lee; Bi-Hwa Wang; Chin-Pang Lee
Journal:  Neuropsychiatr Dis Treat       Date:  2019-01-31       Impact factor: 2.570

3.  An outbreak of food borne illness due to methomyl pesticide intoxication in Korea.

Authors:  Hyo-Wook Gil; Mi-Hye Jeong; Jung Soo Park; Hwan-Won Choi; So-Young Kim; Sae-Yong Hong
Journal:  J Korean Med Sci       Date:  2013-10-31       Impact factor: 2.153

4.  The Anion Gap is a Predictive Clinical Marker for Death in Patients with Acute Pesticide Intoxication.

Authors:  Sun-Hyo Lee; Samel Park; Jung-Won Lee; Il-Woong Hwang; Hyung-Jun Moon; Ki-Hwan Kim; Su-Yeon Park; Hyo-Wook Gil; Sae-Yong Hong
Journal:  J Korean Med Sci       Date:  2016-05-09       Impact factor: 2.153

  4 in total

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