M Makeieff1, J Thariat, E Reyt, C-A Righini. 1. Service d'ORL et de chirurgie cervico-faciale, pôle neuroscience tête et cou, hôpital Gui de Chauliac, CHU de Montpellier, 80, avenue Augustin-Fliche, 34295 Montpellier cedex, France. m-makeieff@chu-montpellier.fr
Abstract
OBJECTIVE: Review of the treatment of cervical paraganglioma. MATERIAL AND METHODS: Review of the literature based on a Medline database. RESULTS: The treatment of choice consists of a multidisciplinary approach based on a detailed clinical, laboratory and radiological work-up. Vascular reconstruction may be necessary when the tumour invades the artery wall. The main complication of surgery is damage to cranial nerves involved in speech and/or swallowing. Treatment of bilateral tumours must be conducted in two stages. The first side to be operated depends on the sites and size of the tumours, as the primary objective is to avoid bilateral vagus nerve palsy. Radiotherapy has been used to treat paragangliomas for several years and achieves tumour stabilization in the majority of cases. Potential indications reported in the literature are: inoperable tumours, recurrence after surgery, some bilateral tumours and malignant tumours. CONCLUSION: Surgery is the standard treatment for cervical paraganglioma. Radiotherapy can be proposed when surgery is contraindicated.
OBJECTIVE: Review of the treatment of cervical paraganglioma. MATERIAL AND METHODS: Review of the literature based on a Medline database. RESULTS: The treatment of choice consists of a multidisciplinary approach based on a detailed clinical, laboratory and radiological work-up. Vascular reconstruction may be necessary when the tumour invades the artery wall. The main complication of surgery is damage to cranial nerves involved in speech and/or swallowing. Treatment of bilateral tumours must be conducted in two stages. The first side to be operated depends on the sites and size of the tumours, as the primary objective is to avoid bilateral vagus nerve palsy. Radiotherapy has been used to treat paragangliomas for several years and achieves tumour stabilization in the majority of cases. Potential indications reported in the literature are: inoperable tumours, recurrence after surgery, some bilateral tumours and malignant tumours. CONCLUSION: Surgery is the standard treatment for cervical paraganglioma. Radiotherapy can be proposed when surgery is contraindicated.
Authors: Barbara Peric; Ziva Pohar Marinsek; Breda Skrbinc; Maja Music; Ivana Zagar; Marko Hocevar Journal: World J Surg Oncol Date: 2014-08-20 Impact factor: 2.754