Literature DB >> 23021036

Spinal metastasis from acinic cell carcinoma of the parotid gland: a case report.

Jason D Zook1, Mladen Djurasovic, John R Dimar, Leah Y Carreon.   

Abstract

BACKGROUND CONTEXT: Acinic cell carcinoma is the fourth most common tumor of the parotid gland, and spinal metastases are thought to be exceedingly rare. Only two other reported presentations are found in the literature, both presumably secondary to incomplete surgical resections.
PURPOSE: To present the first known case of metastasis to the lumbar spine causing vertebral body involvement, after complete resection of the parotid gland. STUDY
DESIGN: Case report.
METHODS: A case of a patient who presented with low back pain and had imaging studies showing an expansive destructive lesion of the L4 vertebral body. The patient underwent a radical parotidectomy and radiation therapy for dedifferentiated, high-grade acinic cell carcinoma 2 years prior.
RESULTS: The patient underwent anterior L4 corpectomy and strut cage placement and posterior pedicle screw fixation from L2 to L5 on the same day, followed by radiation and oral chemotherapy 3 weeks later. Histopathologic examination confirmed metastatic dedifferentiated acinic cell carcinoma, present in the L4 vertebral body and overlying psoas muscle.
CONCLUSIONS: This case report underscores the importance of careful evaluation of patients presenting with back pain with a history of malignancy. It also calls into question the traditional low-grade classification ascribed to these tumors, given their ability to metastasize after complete excision and adjuvant therapy.
Copyright © 2012 Elsevier Inc. All rights reserved.

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Year:  2012        PMID: 23021036     DOI: 10.1016/j.spinee.2012.08.021

Source DB:  PubMed          Journal:  Spine J        ISSN: 1529-9430            Impact factor:   4.166


  4 in total

1.  The etiologies of low back pain in patients with lumbar disk herniation.

Authors:  Fariborz Samini; Mohammad Gharedaghi; Mahdi Khajavi; Mohammad Samini
Journal:  Iran Red Crescent Med J       Date:  2014-10-05       Impact factor: 0.611

2.  Acinic cell carcinoma of the parotid gland: a case report and review of the literature.

Authors:  Ilson Sepúlveda; Michael Frelinghuysen; Enrique Platin; M Loreto Spencer; Alexis Urra; Pablo Ortega
Journal:  Case Rep Oncol       Date:  2015-01-13

3.  Spinal metastasis at the cervicothoracic junction from acinic cell carcinoma of the parotid gland: Case report.

Authors:  Ruy Camilo Gil Rohrmoser; Manuel Diaz Borras; Giovanni López Laínez; Julio Briz Eisen; Luis Linares Martinez; Joaquin Barnoya
Journal:  Surg Neurol Int       Date:  2021-09-20

4.  A rare case of iliac crest metastasis from acinic cell carcinoma of parotid gland.

Authors:  Sergio Sessa; Antonio Ziranu; Giulio Di Giacomo; Almadori Giovanni; Giulio Maccauro
Journal:  World J Surg Oncol       Date:  2014-03-01       Impact factor: 2.754

  4 in total

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