Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Mitochondria and telomeres: the promiscuous roles of TIN2.

Literature DB >> 23020852

Mitochondria and telomeres: the promiscuous roles of TIN2.

Lucas B Sullivan¹, Janine H Santos, Navdeep S Chandel.

Abstract

Telomeric proteins are best known for their role in maintenance of telomere function. In this issue, Chen et al. (2012) demonstrate that the telomeric protein TIN2 can specifically localize to the mitochondria, where it can regulate metabolism and ROS production.

Entities: Chemical Gene

Year: 2012 PMID： 23020852 DOI： 10.1016/j.molcel.2012.09.006

Source DB: PubMed Journal: Mol Cell ISSN： 1097-2765 Impact factor: 17.970

Keyword Cloud
Cited

5 in total

Review 1. Mitochondrial redox system, dynamics, and dysfunction in lung inflammaging and COPD.

Authors: Chad A Lerner; Isaac K Sundar; Irfan Rahman
Journal: Int J Biochem Cell Biol Date: 2016-07-26 Impact factor: 5.085

2. Shortened leukocyte telomere length in type 2 diabetes mellitus: genetic polymorphisms in mitochondrial uncoupling proteins and telomeric pathways.

Authors: Yuling Zhou; Zhixin Ning; Yvonne Lee; Brett D Hambly; Craig S McLachlan
Journal: Clin Transl Med Date: 2016-03-07

Mitochondria and telomeres: the promiscuous roles of TIN2.

Review 1. Mitochondrial redox system, dynamics, and dysfunction in lung inflammaging and COPD.

2. Shortened leukocyte telomere length in type 2 diabetes mellitus: genetic polymorphisms in mitochondrial uncoupling proteins and telomeric pathways.

3. Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening.

4. Loss of RNA-binding protein HuR facilitates cellular senescence through posttranscriptional regulation of TIN2 mRNA.

Review 5. Multisystemic Manifestations in Rare Diseases: The Experience of Dyskeratosis Congenita.